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Statistical study of the relationship between hyperuricemia, dyslipidemia and type 2 diabetes in rural population of Tizi-Ouzou, Algeria

Lefsih, Khalef; Dahmani, Dalila; Cherrad, Rabah; Lalaoui, Souad; Amrara, Sarah


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  <dc:creator>Lefsih, Khalef</dc:creator>
  <dc:creator>Dahmani, Dalila</dc:creator>
  <dc:creator>Cherrad, Rabah</dc:creator>
  <dc:creator>Lalaoui, Souad</dc:creator>
  <dc:creator>Amrara, Sarah</dc:creator>
  <dc:date>2020-08-08</dc:date>
  <dc:description>Aim : The main objective of our work was to assess the relationship between type 2 diabetes, hyperuricemia and dyslipidemia in the population of Tizi-Ouzou. By evaluating the relationship between hyperuricemia and some blood lipid parameters, we thus establish, in type 2 diabetes, the correlation between uremia and these lipid parameters. Subjects and methods:  The survey was carried out by means of an individual questionnaire. We excluded from our study pregnant women, patients with cancer, patients with end-stage renal disease and subjects who did not respond to the questionnaire. Results:  Serum uric acid level increased with age (p = 0.025). Hyperuricemia was associated with heart disease (p = 0.0007). All patients with gout presented an elevated serum uric acid (p = 0.000001). Dyslipidemia was more common in patients with elevated serum uric acid levels (p = 0.0008). Triglyceridemia was significantly associated with hyperuricemia (p = 0.025). The relationship between type 2 diabetes and glomerular filtration rate  was not significant, while the latter was decreased in patients with elevated serum uric acid levels (p = 0.0001). In, stratified analysis, age was effect modifier, the age-dependent results make us understand that resistance to insulin constitutes a significant factor of hyperuricemia. Conclusion: The association between hyperuricemia and dyslipidemia in type 2 diabetes emphasizes that insulin resistance acts on both lipid parameters and uricemia. A diet correcting dyslipidemia may also correct the uricemia.</dc:description>
  <dc:identifier>https://zenodo.org/record/3970038</dc:identifier>
  <dc:identifier>10.5281/zenodo.3970038</dc:identifier>
  <dc:identifier>oai:zenodo.org:3970038</dc:identifier>
  <dc:relation>doi:10.5281/zenodo.3970037</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>https://creativecommons.org/licenses/by/4.0/legalcode</dc:rights>
  <dc:source>The North African Journal of Food and Nutrition Research 04(07) 268-279</dc:source>
  <dc:subject>hyperuricemia</dc:subject>
  <dc:subject>diabetes type 2</dc:subject>
  <dc:subject>dyslipidemia</dc:subject>
  <dc:subject>lipoproteins</dc:subject>
  <dc:title>Statistical study of the relationship between hyperuricemia, dyslipidemia and type 2 diabetes in rural population of Tizi-Ouzou, Algeria</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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