Journal article Open Access

Statistical study of the relationship between hyperuricemia, dyslipidemia and type 2 diabetes in rural population of Tizi-Ouzou, Algeria

Lefsih, Khalef; Dahmani, Dalila; Cherrad, Rabah; Lalaoui, Souad; Amrara, Sarah


Citation Style Language JSON Export

{
  "publisher": "Zenodo", 
  "DOI": "10.5281/zenodo.3970038", 
  "container_title": "The North African Journal of Food and Nutrition Research", 
  "title": "Statistical study of the relationship between hyperuricemia, dyslipidemia and type 2 diabetes in rural population of Tizi-Ouzou, Algeria", 
  "issued": {
    "date-parts": [
      [
        2020, 
        8, 
        8
      ]
    ]
  }, 
  "abstract": "<p><strong>Aim : </strong>The main objective of our work was to assess the relationship between type 2 diabetes, hyperuricemia and dyslipidemia in the population of Tizi-Ouzou. By evaluating the relationship between hyperuricemia and some blood lipid parameters, we thus establish, in type 2 diabetes, the correlation between uremia and these lipid parameters. <strong>Subjects and methods</strong>: &nbsp;The survey was carried out by means of an individual questionnaire. We excluded from our study pregnant women, patients with cancer, patients with end-stage renal disease and subjects who did not respond to the questionnaire. <strong>Results</strong>: &nbsp;Serum uric acid level increased with age (p = 0.025). Hyperuricemia was associated with heart disease (p = 0.0007). All patients with gout presented an elevated serum uric acid (p = 0.000001). Dyslipidemia was more common in patients with elevated serum uric acid levels (p = 0.0008). Triglyceridemia was significantly associated with hyperuricemia (p = 0.025). The relationship between type 2 diabetes and glomerular filtration rate&nbsp; was not significant, while the latter was decreased in patients with elevated serum uric acid levels (p = 0.0001). In, stratified analysis, age was effect modifier, the age-dependent results make us understand that resistance to insulin constitutes a significant factor of hyperuricemia. <strong>Conclusion:</strong> The association between hyperuricemia and dyslipidemia in type 2 diabetes emphasizes that insulin resistance acts on both lipid parameters and uricemia. A diet correcting dyslipidemia may also correct the uricemia.</p>", 
  "author": [
    {
      "family": "Lefsih, Khalef"
    }, 
    {
      "family": "Dahmani, Dalila"
    }, 
    {
      "family": "Cherrad, Rabah"
    }, 
    {
      "family": "Lalaoui, Souad"
    }, 
    {
      "family": "Amrara, Sarah"
    }
  ], 
  "page": "268-279", 
  "volume": "04", 
  "type": "article-journal", 
  "issue": "07", 
  "id": "3970038"
}
22
17
views
downloads
All versions This version
Views 2222
Downloads 1717
Data volume 70.5 MB70.5 MB
Unique views 2121
Unique downloads 1515

Share

Cite as