10.3389/fpsyg.2020.01056
https://zenodo.org/records/3946213
oai:zenodo.org:3946213
Chami, Rayane
Rayane
Chami
0000-0002-4999-3379
Section of Eating Disorders, Department of Psychological Medicine, King's College London, London, United Kingdom
Treasure, Janet
Janet
Treasure
0000-0003-0871-4596
Section of Eating Disorders, Department of Psychological Medicine, King's College London, London, United Kingdom
Cardi, Valentina
Valentina
Cardi
0000-0002-7763-7099
Section of Eating Disorders, Department of Psychological Medicine, King's College London, London, United Kingdom
Lozano-Madrid, María
María
Lozano-Madrid
0000-0003-3833-317X
Department of Psychiatry, Bellvitge University Hospital-Institut d'Investigacio Biomedica de Bellvitge (IDIBELL), Barcelona, Spain
Eichin, Katharina
Katharina
Eichin
Department of Psychology, Division of Health Psychology, Paris-Lodron-University of Salzburg, Salzburg, Austria
McLoughlin, Grainne
Grainne
McLoughlin
0000-0001-5785-9527
Social, Genetic, and Developmental Psychiatry Department, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom In a feasib
Blechert, Jens
Jens
Blechert
0000-0002-3820-109X
Department of Psychology, Division of Health Psychology, Paris-Lodron-University of Salzburg, Salzburg, Austria
Exploring changes in event-related potentials after a feasibility trial of inhibitory training for bulimia nervosa and binge eating disorder.
Zenodo
2020
2020-05-27
Creative Commons Attribution 4.0 International
In a feasibility trial comparing two forms of combined inhibitory control training and goal planning (i.e., food-specific and general) among patients with bulimia nervosa (BN) and binge eating disorder (BED), we found evidence of symptomatic benefit, with stronger effects among participants receiving a food-specific intervention. The aim of the present study was to examine changes in behavioral outcomes and event-related potentials (ERPs; N2 and P3 amplitudes) from baseline to post-intervention that might suggest the mechanisms underpinning these effects. Fifty-five participants completed go/no-go tasks during two electroencephalography (EEG) sessions, at baseline and post-intervention. The go/no-go task included “go” cues to low energy-dense foods and non-foods, and “no-go” cues to high energy-dense foods and non-foods. Datasets with poor signal quality and/or outliers were excluded, leaving 48 participants (N = 24 BN; N = 24 BED) in the analyses. Participants allocated to the food-specific, compared to the general intervention group, showed significantly greater reductions in reaction time to low energy-dense foods, compared to non-foods, by post-intervention. Commission errors significantly increased from baseline to post-intervention, regardless of stimulus type (food vs. non-food) and intervention group (food-specific vs. general). There were no significant changes in omission errors. P3 amplitudes to “no-go” cues marginally, but non-significantly, decreased by post-intervention, but there was no significant interaction with stimulus type (high energy-dense food vs. non-food) or intervention group (food-specific vs. general). There were no significant changes in N2 amplitudes to “no-go” cues, N2 amplitudes to “go” cues, or P3 amplitudes to “go” cues from baseline to post-intervention. Training effects were only marginally captured by these event-related potentials. We discuss limitations to the task paradigm, including its two-choice nature, ease of completion, and validity, and give recommendations for future research exploring ERPs using inhibitory control paradigms.