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Genetic Variability at the Catalytic Site of the Papain-like Protease and the Predicted Effects of Mutations on the binding of the Inhibitor VIR251

Yazdani, Setayesh; Schapira, Matthieu; De Maio, Nicola


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  <identifier identifierType="DOI">10.5281/zenodo.3912031</identifier>
  <creators>
    <creator>
      <creatorName>Yazdani, Setayesh</creatorName>
      <givenName>Setayesh</givenName>
      <familyName>Yazdani</familyName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-9205-4318</nameIdentifier>
      <affiliation>Structural Genomics Consortium</affiliation>
    </creator>
    <creator>
      <creatorName>Schapira, Matthieu</creatorName>
      <givenName>Matthieu</givenName>
      <familyName>Schapira</familyName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-1047-3309</nameIdentifier>
      <affiliation>Structural Genomics Consortium</affiliation>
    </creator>
    <creator>
      <creatorName>De Maio, Nicola</creatorName>
      <givenName>Nicola</givenName>
      <familyName>De Maio</familyName>
      <affiliation>European Bioinformatics Institute</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Genetic Variability at the Catalytic Site of the Papain-like Protease and the Predicted Effects of Mutations on the binding of the Inhibitor VIR251</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2020</publicationYear>
  <subjects>
    <subject>SARS-CoV-2</subject>
    <subject>papain-like protease</subject>
    <subject>Genetic variability</subject>
    <subject>PLPro</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2020-06-28</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Other</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/3912031</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.3912030</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/covid-19</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/zenodo</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;This document outlines the method for finding the catalytic pocket of SARS-CoV-2 papain-like protease and assessing its genetic variability across coronaviruses and more than 15,000 SARS-CoV-2 samples.&amp;nbsp;&lt;/p&gt;

&lt;p&gt;&amp;nbsp;&lt;/p&gt;</description>
  </descriptions>
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