Bogdan Feliks Kania*
Urszula Bracha
2020-06-24
<p>AbstractNeuropathic pain is serious therapeutic problem. Current therapy is often ineffective and the available drugs have serious side ef-fects. For these reasons, the search for alternative therapeutic solutions is underway. Recent research on metabotropic receptors for glutamic acid (mGluR) gives great hope for the development of a new type of drug in the treatment of neuropathic pain. Particularly promising are antagonists of mGluR group I receptors. There are numerous studies demonstrating the efficacy of non-competitive mGlu1 and mGlu5 receptor antagonists in animal models of neuropathic pain. The purpose of this review article is to gather informa-tion obtained from research on the role of mGluR antagonists in neuropathic pain.</p>
https://doi.org/10.5281/zenodo.3906136
oai:zenodo.org:3906136
eng
Zenodo
https://doi.org/10.5281/zenodo.3906135
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Archives of Veterinary and Animal Sciences, 2(2), 1-8, (2020-06-24)
Keywords: Neuropathic pain; Glutamate; mGluR antagonists
The Neuropathic Pain in Animals
info:eu-repo/semantics/article