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FucoSan: Extraction of fucoidans from different brown algae species using different methods and their chemical and biological characterization

Neupane, Sandesh; Bittkau, Kaya Saskia; Sandow, Verena; Ptak, Signe; Mikkelsen, Maria Dalgaard; Dörschmann, Philipp; Ohmes, Julia; Frette, Xavier; Meyer, Anne S.; Fuchs, Sabine; Klettner, Alexa; Alban, Susanne


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    "doi": "10.5281/zenodo.3876379", 
    "description": "<p>This is a dataset extracted from the database of the Interreg project &ldquo;FucoSan &ndash; Health from the sea&rdquo; which includes information on the used algae species, the extraction of fucoidans as well as their chemical and pharmacological characterization.</p>\n\n<p>Macroalgae represent a vast source of renewable raw materials for research, development and application. An example of current high interest are fucoidans from brown algae. These fucose-containing sulfated polysaccharides exhibit a multitude of bioactivities offering attractive options for applications in medicine and cosmetics. The composition and chemical structure of fucoidans and thus their bioactivities may, however, largely vary depending on the algae species, extraction procedure and many other factors. Therefore, much research is still needed in the range from the algal source up to the targeted development of fucoidans optimized for respective applications. Since 2017, this is the topic of the Danish-German project Interreg project &ldquo;FucoSan &ndash; health from the Sea&rdquo; involving 11 partners with different expertise. Here, the current state of the fucoidan series produced and explored within the project is presented including information on the used algae species and batches, the extraction, purification and fractionation of the fucoidans as well as their chemical and pharmacological characterization. Based on their basic pharmacological activities, fucoidans are then selected and further tested in advanced experiments for specific applications in medicine and cosmetics.</p>", 
    "language": "eng", 
    "title": "FucoSan: Extraction of fucoidans from different brown algae species using different methods and their chemical and biological characterization", 
    "license": {
      "id": "CC-BY-4.0"
    }, 
    "notes": "https://www.fucosan.eu\nFunding reference: FucoSan is funded by Interreg Deutschland-Danmark with means from the European Regional Development Fund.", 
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    "version": "1.0.0", 
    "keywords": [
      "fucoidan", 
      "brown seaweed", 
      "regenerative medicine", 
      "opthalmology", 
      "chemical characteristics"
    ], 
    "publication_date": "2020-06-05", 
    "creators": [
      {
        "orcid": "0000-0002-5167-9848", 
        "affiliation": "Pharmaceutical Institute, Kiel University, Kiel, Germany", 
        "name": "Neupane, Sandesh"
      }, 
      {
        "affiliation": "Pharmaceutical Institute, Kiel University, Kiel, Germany", 
        "name": "Bittkau, Kaya Saskia"
      }, 
      {
        "affiliation": "Coastal Research & Management oHG, Kiel Germany", 
        "name": "Sandow, Verena"
      }, 
      {
        "affiliation": "University of Southern Denmark, Odense, Denmark", 
        "name": "Ptak, Signe"
      }, 
      {
        "affiliation": "Technical University of Denmark, Lyngby, Denmark", 
        "name": "Mikkelsen, Maria Dalgaard"
      }, 
      {
        "affiliation": "University Hospital Schleswig-Holstein \u2013 Department of Ophthalmology, Kiel, Germany", 
        "name": "D\u00f6rschmann, Philipp"
      }, 
      {
        "affiliation": "University Hospital Schleswig-Holstein - Trauma Surgery, Kiel Germany", 
        "name": "Ohmes, Julia"
      }, 
      {
        "affiliation": "University of Southern Denmark, Odense, Denmark", 
        "name": "Frette, Xavier"
      }, 
      {
        "affiliation": "Technical University of Denmark, Lyngby, Denmark", 
        "name": "Meyer, Anne S."
      }, 
      {
        "affiliation": "University Hospital Schleswig-Holstein - Trauma Surgery, Kiel Germany", 
        "name": "Fuchs, Sabine"
      }, 
      {
        "affiliation": "University Hospital Schleswig-Holstein \u2013 Department of Ophthalmology, Kiel, Germany", 
        "name": "Klettner, Alexa"
      }, 
      {
        "affiliation": "Pharmaceutical Institute, Kiel University, Kiel, Germany", 
        "name": "Alban, Susanne"
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