Dataset Open Access

Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection

Anastasia A. Minervina; Ekaterina A. Komech; Aleksei Titov; Meriem Bensouda Koraichi; Elisa Rosati; Ilgar Z. Mamedov; Andre Franke; Grigory A. Efimov; Dmitriy M. Chudakov; Thierry Mora; Aleksandra M. Walczak; Yury B. Lebedev; Mikhail V. Pogorelyy


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  <dc:creator>Anastasia A. Minervina</dc:creator>
  <dc:creator>Ekaterina A. Komech</dc:creator>
  <dc:creator>Aleksei Titov</dc:creator>
  <dc:creator>Meriem Bensouda Koraichi</dc:creator>
  <dc:creator>Elisa Rosati</dc:creator>
  <dc:creator>Ilgar Z. Mamedov</dc:creator>
  <dc:creator>Andre Franke</dc:creator>
  <dc:creator>Grigory A. Efimov</dc:creator>
  <dc:creator>Dmitriy M. Chudakov</dc:creator>
  <dc:creator>Thierry Mora</dc:creator>
  <dc:creator>Aleksandra M. Walczak</dc:creator>
  <dc:creator>Yury B. Lebedev</dc:creator>
  <dc:creator>Mikhail V. Pogorelyy</dc:creator>
  <dc:date>2020-05-20</dc:date>
  <dc:description>Processed TCRbeta and TCRalpha repertoires after mild COVID-19 infection, see preprint: https://www.biorxiv.org/content/10.1101/2020.05.18.100545v1

and GitHub repository: https://github.com/pogorely/Minervina_COVID

Two donors (M and W), two biological replicates of PBMC (F1 and F2), CD4+, CD8+, and Memory subpopulations for each post-infection time points (day 15, 30, 37, 45 post-infection), and pre-infection PBMC repertoires sampled in 2019 and 2018. </dc:description>
  <dc:description>Demultiplexing and UMI-consenuses were done with migec (v. 1.2.7), alignments and assembly of UMI-consensuses into clonotypes performed with mixcr (v. 2.1.11).</dc:description>
  <dc:identifier>https://zenodo.org/record/3835956</dc:identifier>
  <dc:identifier>10.5281/zenodo.3835956</dc:identifier>
  <dc:identifier>oai:zenodo.org:3835956</dc:identifier>
  <dc:relation>url:https://www.biorxiv.org/content/10.1101/2020.05.18.100545v1</dc:relation>
  <dc:relation>url:https://github.com/pogorely/Minervina_COVID</dc:relation>
  <dc:relation>doi:10.5281/zenodo.3835955</dc:relation>
  <dc:relation>url:https://zenodo.org/communities/covid-19</dc:relation>
  <dc:relation>url:https://zenodo.org/communities/zenodo</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://creativecommons.org/licenses/by/4.0/legalcode</dc:rights>
  <dc:subject>TCR</dc:subject>
  <dc:subject>RepSeq</dc:subject>
  <dc:subject>COVID</dc:subject>
  <dc:title>Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection</dc:title>
  <dc:type>info:eu-repo/semantics/other</dc:type>
  <dc:type>dataset</dc:type>
</oai_dc:dc>
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