10.1186/s12955-020-01312-4
https://zenodo.org/records/3831523
oai:zenodo.org:3831523
Rieckmann, Nina
Nina
Rieckmann
Institute of Public Health, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Neumann, Konrad
Konrad
Neumann
Institute of Public Health, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Feger, Sarah
Sarah
Feger
Department of Radiology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Ibes, Paolo
Paolo
Ibes
Department of Radiology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Napp, Adriane
Adriane
Napp
Department of Radiology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Preuß, Daniel
Daniel
Preuß
Department of Radiology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Dreger, Henryk
Henryk
Dreger
Department of Cardiology and Angiology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Feuchtner, Gudrun
Gudrun
Feuchtner
Department of Radiology, Innsbruck Medical University, Innsbruck, Austria
Plank, Fabian
Fabian
Plank
Department of Internal Medicine III, Cardiology, Innsbruck Medical University, Innsbruck, Austria
Suchánek, Vojtěch
Vojtěch
Suchánek
Department of Imaging Methods, Motol University Hospital, Prague, Czech Republic
Veselka, Josef
Josef
Veselka
Department of Cardiology, Motol University Hospital, Prague, Czech Republic
Engstrøm, Thomas
Thomas
Engstrøm
Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Kofoed, Klaus F.
Klaus F.
Kofoed
Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Schröder, Stephen
Stephen
Schröder
Department of Cardiology, ALB FILS KLINIKEN GmbH, Goeppingen, Germany
Zelesny, Thomas
Thomas
Zelesny
Department of Radiology, ALB FILS KLINIKEN GmbH, Goeppingen, Germany
Gutberlet, Matthias
Matthias
Gutberlet
Department of Radiology, University of Leipzig Heart Centre, Leipzig, Germany
Woinke, Michael
Michael
Woinke
Department of Cardiology, University of Leipzig Heart Centre, Leipzig, Germany
Maurovich-Horvat, Pál
Pál
Maurovich-Horvat
Heart and Vascular Center, Semmelweis University, Budapest, Hungary
Merkely, Béla
Béla
Merkely
Heart and Vascular Center, Semmelweis University, Budapest, Hungary
Donnelly, Patrick
Patrick
Donnelly
Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, UK
Ball, Peter
Peter
Ball
Department of Radiology, Southeastern Health and Social Care Trust, Belfast, UK
Dodd, Jonathan D.
Jonathan D.
Dodd
Department of Radiology, St. Vincent's University Hospital, Dublin, Ireland
Hensey, Mark
Mark
Hensey
Department of Cardiology, St. Vincent's University Hospital, Dublin, Ireland
Loi, Bruno
Bruno
Loi
Department of Cardiology, Azienda Ospedaliera Brotzu, Cagliari, CA, Italy
Saba, Luca
Luca
Saba
Department of Radiology, University of Cagliari, Cagliari, CA, Italy
Francone, Marco
Marco
Francone
Department of Radiological, Pathological and Oncological Sciences, Sapienza University of Rome, Rome, Italy
Mancone, Massimo
Massimo
Mancone
Department of Cardiovascular, Respiratory, Nephrology, Anesthesiology and Geriatric Science, Sapienza University of Rome, Rome, Italy
Berzina, Marina
Marina
Berzina
Department of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia
Erglis, Andrejs
Andrejs
Erglis
Department of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia
Vaitiekiene, Audrone
Audrone
Vaitiekiene
Department of Cardiology, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania
Zajanckauskiene, Laura
Laura
Zajanckauskiene
Department of Cardiology, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania
Harań, Tomasz
Tomasz
Harań
Department of Radiology, Wojewodzki Szpital Specjalistyczny We Wroclawiu, Wroclaw, Poland
Suckiel, Malgorzata Ilnicka
Malgorzata Ilnicka
Suckiel
Department of Cardiology, Wojewodzki Szpital Specjalistyczny We Wroclawiu, Wroclaw, Poland
Faria, Rita
Rita
Faria
Department of Cardiology, Centro Hospitalar de Vila Nova de Gaia/ Espinho, Vila Nova de Gaia, Portugal
Gama-Ribeiro, Vasco
Vasco
Gama-Ribeiro
Department of Cardiology, Centro Hospitalar de Vila Nova de Gaia/ Espinho, Vila Nova de Gaia, Portugal
Benedek, Imre
Imre
Benedek
Center of Advanced Research in Multimodality Cardiac Imaging, Cardio Med Medical Center, Tirgu Mures, Romania
Rodean, Ioana
Ioana
Rodean
Center of Advanced Research in Multimodality Cardiac Imaging, Cardio Med Medical Center, Tirgu Mures, Romania
Adjić, Filip
Filip
Adjić
Department of Cardiology, Institute for Cardiovascular Diseases of Vojvodina, Novi Sad, Sremska Kamenica, Serbia
Čemerlić Adjić, Nada
Nada
Čemerlić Adjić
Department of Cardiology, Institute for Cardiovascular Diseases of Vojvodina, Novi Sad, Sremska Kamenica, Serbia
Rodriguez-Palomares, José
José
Rodriguez-Palomares
Department of Cardiology, Hospital Universitari Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Garcia del Blanco, Bruno
Bruno
Garcia del Blanco
Department of Cardiology, Hospital Universitari Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Brooksbank, Katriona
Katriona
Brooksbank
BHF Centre of Research Excellence, Glasgow University, Glasgow, UK
Collison, Damien
Damien
Collison
Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, UK
Davis, Gershan
Gershan
Davis
Cardiovascular Medicine, University of Central Lancashire, Preston, UK
Thwaite, Erica
Erica
Thwaite
Department of Radiology, Aintree University Hospital, Liverpool, UK
Knuuti, Juhani
Juhani
Knuuti
Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland
Saraste, Antti
Antti
Saraste
Heart Center, Turku University Hospital and University of Turku, Turku, Finland
Kępka, Cezary
Cezary
Kępka
The National Institute of Cardiology, Warsaw, Poland
Kruk, Mariusz
Mariusz
Kruk
The National Institute of Cardiology, Warsaw, Poland
Benedek, Theodora
Theodora
Benedek
Department of Internal Medicine, University of Medicine and Pharmacy, Tirgu Mures, Romania
Ratiu, Mihaela
Mihaela
Ratiu
County Clinical Emergency Hospital, Tirgu Mures, Romania
Neskovic, Aleksandar N.
Aleksandar N.
Neskovic
Clinic of Internal medicine/Interventional cardiology, Clinical Hospital Center Zemun-Belgrade, Belgrade, Serbia
Vidakovic, Radosav
Radosav
Vidakovic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Diez, Ignacio
Ignacio
Diez
Department of Cardiology, Basurto Hospital, Bilbao, Spain
Lecumberri, Iñigo
Iñigo
Lecumberri
Department of Radiology, Basurto Hospital, Bilbao, Spain
Fisher, Michael
Michael
Fisher
Department of Cardiology, Royal Liverpool University Hospital, Liverpool, UK
Ruzsics, Balasz
Balasz
Ruzsics
Department of Cardiology, Royal Liverpool University Hospital, Liverpool, UK
Hollingworth, William
William
Hollingworth
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
Gutiérrez-Ibarluzea, Iñaki
Iñaki
Gutiérrez-Ibarluzea
Osteba, Basque Office for Health Technology Assessment, Ministry for Health, Basque Country, Spain
Dewey, Marc
Marc
Dewey
Department of Radiology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Müller-Nordhorn, Jacqueline
Jacqueline
Müller-Nordhorn
Institute of Public Health, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain
Zenodo
2020
Chest pain
Angina
Coronary artery disease
Computed tomography angiography
Invasive coronary angiography
Health-related quality of life
2020-05-14
https://zenodo.org/communities/fp7-bmc
https://zenodo.org/communities/eu
Creative Commons Attribution 4.0 International
Background: Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD.
Methods: From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 ± 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale.
Results: Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 ± 8.8, 43.3 ± 9.1, 46.2 ± 9.0, 46.4 ± 11.4, respectively, all age and gender-adjusted p < 0.01), and highest anxiety levels (8.3 ± 4.1, 7.5 ± 4.1, 6.5 ± 4.0, 4.7 ± 4.5, respectively, all adjusted p < 0.01). On all other measures, patients with typical or atypical angina had lower HRQoL compared to the two other groups (all adjusted p < 0.05). HRQoL did not differ between patients with and without obstructive CAD while women had worse HRQoL compared with men, irrespective of age and angina type.
Conclusions: Prior to a diagnostic procedure for stable chest pain, HRQoL is associated with chest pain characteristics, but not with obstructive CAD, and is significantly lower in women.
Trial registration: Clinicaltrials.gov, NCT02400229.
European Commission
10.13039/501100000780
603266
Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease: Comparative Effectiveness Research of Existing Technologies