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Constructing a Human Atrial Fibre Atlas, Roney et al.

Roney, Caroline


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        <foaf:givenName>Caroline</foaf:givenName>
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    <dct:title>Constructing a Human Atrial Fibre Atlas, Roney et al.</dct:title>
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    <dcat:keyword>Atrial Fibrillation, Atrial Fibres, Mesh, Finite Elements, Electrophysiology, Computational Models</dcat:keyword>
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    <dct:description>&lt;p&gt;&lt;strong&gt;Background:&lt;/strong&gt;&amp;nbsp;Atrial anisotropy affects electrical propagation patterns, anchor locations of atrial reentrant drivers, and atrial mechanics. However, patient-specific atrial fibre fields and anisotropy measurements are not currently available, and consequently assigning fibre fields to atrial models is challenging. We aimed to construct an atrial fibre atlas from a high-resolution DTMRI dataset that optimally reproduces electrophysiology simulation predictions corresponding to patient-specific fibre fields, and to develop a methodology for automatically assigning fibres to patient-specific anatomies.&lt;/p&gt; &lt;p&gt;&amp;nbsp;&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Dataset Description:&lt;/strong&gt;&amp;nbsp;We include&amp;nbsp;endocardial and epicardial left and right atrial surfaces for each of the 7 anatomies included in our study (Constructing a Human Atrial Fibre Atlas, ABME, 2020),&amp;nbsp;together with their fibre fields. We also include&amp;nbsp;the average fibre field for each of the atrial surfaces displayed on anatomy number 6 (named *_A).&amp;nbsp;&lt;/p&gt; &lt;p&gt;For each of the surfaces, we also include universal atrial coordinate fields alpha and beta, which are a lateral-septal coordinate and posterior-anterior coordinate for the LA (IVC-SVC coordinate for the RA). More details on the coordinate construction are given in our manuscript and&amp;nbsp;&lt;a href="https://www.ncbi.nlm.nih.gov/pubmed/31026761"&gt;https://www.ncbi.nlm.nih.gov/pubmed/31026761&lt;/a&gt;. These coordinates can be used for registering datasets.&amp;nbsp;&lt;/p&gt; &lt;p&gt;These meshes are in vtk format, consisting of the nodes, triangular elements, the atrial coordinate fields defined on the nodes, and the fibre field defined on the elements.&amp;nbsp;&lt;/p&gt; &lt;p&gt;We have also included mesh files for the Cardiac Arrhythmia Research Package simulator. These are a list of nodal coordinates (.pts file), a list of triangular elements (.elem file), and a fibre file (.lon). More details on this file format and the carpentry simulator are available at:&amp;nbsp;&lt;a href="https://carpentry.medunigraz.at/carputils/index.html"&gt;https://carpentry.medunigraz.at/carputils/index.html&lt;/a&gt;.&amp;nbsp;&lt;/p&gt;</dct:description>
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    <dct:identifier rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MR/S015086/1</dct:identifier>
    <dct:title>Predicting Atrial Fibrillation Mechanisms Through Deep Learning</dct:title>
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    <dct:title>Personalised Model Based Optimal Lead Guidance in Cardiac Resynchronisation Therapy</dct:title>
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