Fatty acid composition of common bugle herb (ajuga reptans l.)
Creators
- 1. Ivano- Frankivsk National Medical University
- 2. Ivano-Frankivsk National Medical University
Description
Aim. Identification and determination of the qualitative composition and quantitative content of fatty acids in the grass of Ajuga reptans.
Methods of the research. The study of Ajuga reptans fatty acids was carried out by gas chromatography-mass spectrometry, which is based on the formation of fatty acid methyl esters with their subsequent determination.
Results. The method of chromatography-mass spectrometry was the first to study the fatty acid composition of (Ajuga reptans L.). As a result of a study in the herb of Ajuga reptans , 22 substances were identified, of which 9 fatty acids were identified. The quantitative content was dominated by polyunsaturated fatty acids - linolenic and linoleic and saturated - palmitic. Their total content in terms of the sum of fatty acids was 56.71 % (unsaturated), 28.18 % saturated. A small amount of following substances was detected - stearic, eicosanoic, tetracosanoic, behenic acid (6.65 %).
Conclusions. Fatty acids are important biocompounds, which are involved in complex metabolic processes, are important components of lipids and cell membranes in the form of phospholipids, thereby have a large biological role.
Unsaturated fatty acids were found in significant quantities in the herb of common bugle, the amount of which was 4706.78 mg / kg, which was almost 1.4 times higher than the amount of saturated fatty acids (3380.83 mg / kg). The research results can be used in the development of quality control methods for common bugle raw materials and the preparation of biologically active substances from the studied raw materials
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References
- Barbarych, A. I., Bradis, Ye. M., Visiulin, O. D.; Zerov, D. K. (Ed.) (1965). Vyznachnyk roslyn Ukrainy. Kyiv: Urozhai, 875.
- Hrodzinskyi, A. M. (Ed.) (1990). Likarski roslyny. Kyiv: Holov. red. URE, 544.
- Qing, X., Yan, H.-M., Ni, Z.-Y., Vavricka, C. J., Zhang, M.-L., Shi, Q.-W. et. al. (2017). Chemical and pharmacological research on the plants from genus Ajuga. Heterocyclic Communications, 23 (4), 245–268. doi: http://doi.org/10.1515/hc-2017-0064
- Ványolós, A., Simon, A., Tóth, G., Polgár, L., Kele, Z., Ilku, A. et. al. (2009). C-29 Ecdysteroids fromAjuga reptansvar.reptans. Journal of Natural Products, 72 (5), 929–932. doi: http://doi.org/10.1021/np800708g
- Sahakyan, N. Zh., Petrosyan, M. Т., Volodin, V. V., Volodina, S. O., Aghajanyan, J. A., Popov, Yu. G. (2008). Isolated culture of Ajuga genevensis L. as a potential source of biological active substances. New Armenian Medical Journal, 2 (4), 65–74.
- Makhlaiuk, V. P. (1991). Lekarstvennye rasteniia v narodnoi medicine. Moscow: Voennoe izdatelstvo, 148–149.
- Toiu, A., Mocan, A., Vlase, L., Pârvu, A. E., Vodnar, D. C., Gheldiu, A.-M. et. al. (2018). Phytochemical Composition, Antioxidant, Antimicrobial and in Vivo Anti-inflammatory Activity of Traditionally Used Romanian Ajuga laxmannii (Murray) Benth. ("Nobleman's Beard" – Barba Împăratului). Frontiers in Pharmacology, 9. doi: http://doi.org/10.3389/fphar.2018.00007
- Atay, I., Kirmizibekmez, H., Kaiser, M., Akaydin, G., Yesilada, E., Tasdemir, D. (2016). Evaluation ofin vitroantiprotozoal activity ofAjuga laxmanniiand its secondary metabolites. Pharmaceutical Biology, 54 (9), 1808–1814. doi: http://doi.org/10.3109/13880209.2015.1129542
- Ramazanov, N. S. (2005). Phytoecdysteroids and Other Biologically Active Compounds from Plants of the Genus Ajuga. Chemistry of Natural Compounds, 41 (4), 361–369. doi: http://doi.org/10.1007/s10600-005-0153-4
- Doneckaia, E. (2017). Lekarstvennye rasteniia v bytu, medicine, kosmetike. Opisanie rastenii, vyraschivanie i sbor, sroki khraneniia, pokazaniia, recepty, protivopokazaniia, kosmetika. Vol. 3. Moscow, 496.
- Hrytsyniak, I. I., Smolianinov, K. B., Vudmaska, I. V., Yanovych, D. O., Ivaniak, V. V., Halias, H. M. (2010). Biolohichna diia polinenasychenykh N- 3-zhyrnykh kyslot v orhanizmi liudyny ta osnovni dzherela zabezpechennia yikh potreby. Biolohiia tvaryn, 12 (2), 34–40.
- Yushchyshena, O. V., Tsurkan, O. O., Korablova, O. A. (2014). Zhyrni kysloty lystia , stebel ta sutsvit viteksu sviashchennoho (Vitex agnus-castus L.). Zdobutky klinichnoi i eksperymentalnoi medytsyny, 1, 139–141.
- Mamedova, S. O., Pavlii, O. I. (2011). Vyvchennia lipofilnykh spoluk vehetatyvnykh orhaniv sunytsi lisovoi. Medychna khimiia, 13 (3), 44–46.
- Mozaffarian, D. (2005). Does alpha-linolenic acid intake reduce the risk of coronary heart disease? A review of the evidence. Alternative therapies in health and medicine, 11, 24–30.
- Frezza, C., Venditti, A., Pizzoli, F., Serafini, I., Ciccòla, A., Pitorri, M. et. al. (2018). Essential oil composition and total metabolite content of a chemotype of Ajuga reptans L. (Lamiaceae) collected in Central Italy. Plant Biosystems – An International Journal Dealing with All Aspects of Plant Biology, 153 (4), 552–558. doi: http://doi.org/10.1080/11263504.2018.1515121
- Ghita, G., Cioanca, O., Gille, E., Necula, R., Zamfirache, M. M., Stanescu, U. (2011). Contributions to the phytochemical study of some samples of Ajuga reptans L. and Ajuga genevensis L. Bulletin of the Transilvania University of Braşov. Series VI: Medical Sciences, 4 (2 (53)), 7–14.
- De Sousa, D. P. (2011). Analgesic-like Activity of Essential Oils Constituents. Molecules, 16 (3), 2233–2252. doi: http://doi.org/10.3390/molecules16032233
- Lisec, J., Schauer, N., Kopka, J., Willmitzer, L., Fernie, A. R. (2006). Gas chromatography mass spectrometry–based metabolite profiling in plants. Nature Protocols, 1 (1), 387–396. doi: http://doi.org/10.1038/nprot.2006.59
- Vahedi, H., Lari, J., Halimi, M., Nasrabadi, M., Vahedi, A. (2012). Chemical Composition of the n-Hexane Extract ofVerbascum speciosumGrowing Wild in Iran. Journal of Essential Oil Bearing Plants, 15 (6), 895–899. doi: http://doi.org/10.1080/0972060x.2012.10662591
- Sahakyan, N. Z., Petrosyan, M. T., Popov, Y. G., Volodin, V. V., Matistov, N. V., Gruzdev, I. V., Shirshova, T. I. (2010). Content of Neutral Lipids and Fatty Acids in Callus Cultures and Leaves of Intact Plants ofAjuga GenevensisandAjuga Chia. Biotechnology & Biotechnological Equipment, 24 (1), 87–90. doi: http://doi.org/10.1080/13102818.2010.10817817