3632503
doi
10.5281/zenodo.3632503
oai:zenodo.org:3632503
Ayat Ahmed Alrasheid
Pharmacognosy Department, Faculty of Pharmacy, University of Medical Sciences and Technology, Khartoum, Sudan
Saad Mohammed Hussein Ayoub
Pharmacognosy Department, Faculty of Pharmacy, University of Medical Sciences and Technology, Khartoum, Sudan
Phytochemical screening, Antioxidant and Anti Fungal activities of Certain Sudanese Medicinal Plants against Tinea capitis
Sadig George Sadig
Pharmacognosy Department, Faculty of Pharmacy, University of Medical Sciences and Technology, Khartoum, Sudan
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Tinea capitis, antifungal activity, antioxidant activity, Sudan, Lawsonia inermis, Aloe vera, Senna alata.
<p><strong>Herbal medicines have been widely utilized as effective remedies for the prevention and treatment of multiple health conditions for centuries by almost every known culture. A significant fraction of the drugs are either natural products or derived from natural products. This study investigates the antifungal activity of <em>Lawsonia inermis, Aloe vera</em> and <em>Senna alata</em> against <em>Tinea capitis</em>. <em>Tinea capitis</em> is a superficial fungal infection (ring worm) that causes hair fall in specific parts of the head. The main objective of this study was to compare between the antimicrobial effects of the plants extracts on two<em> Tinea capitis</em> subspecies, as well as to detect the phytochemical constituents of each and their antioxidant activity. Fungal strains were isolated from patients and identified using microscopical examination and biochemical tests. All three samples were extracted with ethanol 96% and phytochemical constituents were detected using qualitative standard methods. Anti-microbial activity of three samples extracts with different concentrations was determined using Disc diffusion method and the inhibition zones were measured. The three plants were also screened for their antioxidant activity and gave positive results against the <em>T.capitis</em> species provided (<em>T.verrucosm</em> and <em>T.rubrum</em>). <em>S.alata</em> showed the highest activity against two species with slight difference followed by the L.<em>inermis</em> and<em> A.vera</em> respectively compared with the standard drug fluconazole.</strong></p>
Zenodo
2020-01-31
info:eu-repo/semantics/article
3632502
1580498451.058746
529893
md5:e84920e7dff08df6b3d270b305b3893f
https://zenodo.org/records/3632503/files/Sadig et al.pdf
public
10.5281/zenodo.3632502
isVersionOf
doi