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Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation

Stevens, Alexandra M.; Xiang, Michael; Heppler, Lisa N.; Tosic, Isidora; Jiang, Kevin; Munoz, Jaime O.; Gaikwad, Amos S.; Horton, Terzah M.; Long, Xin; Narayanan, Padmini; Seashore, Elizabeth L.; Terrell, Maci C.; Rashid, Raushan; Krueger, Michael J.; Mangubat-Medina, Alicia E.; Ball, Zachary T.; Sumazin, Pavel; Walker, Sarah R.; Hamada, Yoshimasa; Oyadomari, Seiichi; Redell, Michele S.; Frank, David A.


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@article{stevens_alexandra_m_2020_3626689,
  author       = {Stevens, Alexandra M. and
                  Xiang, Michael and
                  Heppler, Lisa N. and
                  Tosic, Isidora and
                  Jiang, Kevin and
                  Munoz, Jaime O. and
                  Gaikwad, Amos S. and
                  Horton, Terzah M. and
                  Long, Xin and
                  Narayanan, Padmini and
                  Seashore, Elizabeth L. and
                  Terrell, Maci C. and
                  Rashid, Raushan and
                  Krueger, Michael J. and
                  Mangubat-Medina, Alicia E. and
                  Ball, Zachary T. and
                  Sumazin, Pavel and
                  Walker, Sarah R. and
                  Hamada, Yoshimasa and
                  Oyadomari, Seiichi and
                  Redell, Michele S. and
                  Frank, David A.},
  title        = {{Atovaquone is active against AML by upregulating 
                   the integrated stress pathway and suppressing
                   oxidative phosphorylation}},
  journal      = {Blood Adv},
  year         = 2020,
  volume       = 3,
  number       = 24,
  pages        = {4215–4227},
  month        = jan,
  doi          = {10.1182/bloodadvances.2019000499},
  url          = {https://doi.org/10.1182/bloodadvances.2019000499}
}
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