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Jaqpot 5: How to simulate biodistribution scenarios using custom PBPK models

Haralambos Sarimveis


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{
  "description": "<p>Jaqpot 5 is a user-friendly web-based e-infrastructure that allows model developers to deploy their predictive models and share them through the web. The Jaqpot 5 GUI&nbsp; directs the model developers to further document their models in a way that can be easily understood and used by end-users with little or no experience on machine learning and statistical analysis.&nbsp;&nbsp; The GUI also allows the end-users to apply the models on their own data for validation and/or prediction purposes and the results are collected and visualised in automatically generated tables, graphs and reports. All major machine learning and statistical data-driven algorithms are supported in Jaqpot 5,&nbsp; by integrating popular libraries such as the Python Scikit-learn and the R Caret libraries. Jaqpot 5 has been designed as a generic modelling and machine learning web platform, but particular emphasis is given on serving the needs of the chemo/bio/nano/pharma/ communities by integrating QSAR, biokinetics, dose-response and read-across models.&nbsp; Jaqpot 5 has been developed by the <a href=\"https://www.chemeng.ntua.gr/labs/control_lab/index.html\">Unit of Process Control and Informatics</a> in the School of Chemical Engineering at the National Technical University of Athens.</p>\n\n<p>&nbsp;</p>\n\n<p>This document provides a tutorial for simulating biodistribution scenarios using custom PBPK models that have been deployed on Jaqpot5. The resource has been made available at <a href=\"https://app.jaqpot.org/\">https://app.jaqpot.org/</a>.</p>", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "creator": [
    {
      "affiliation": "School of Chemical Engineering", 
      "@type": "Person", 
      "name": "Haralambos Sarimveis"
    }
  ], 
  "url": "https://zenodo.org/record/3610182", 
  "datePublished": "2020-01-16", 
  "keywords": [
    "Machine learning", 
    "Biokinetics", 
    "ChemInformatics", 
    "NanoInformatics"
  ], 
  "contributor": [
    {
      "affiliation": "School of Chemical Engineering", 
      "@id": "https://orcid.org/0000-0002-8607-9965", 
      "@type": "Person", 
      "name": "Haralambos Sarimveis"
    }, 
    {
      "affiliation": "School of Chemical Engineering", 
      "@type": "Person", 
      "name": "Pantelis Karatzas"
    }, 
    {
      "affiliation": "School of Chemical Engineering", 
      "@id": "https://orcid.org/0000-0002-0628-8434", 
      "@type": "Person", 
      "name": "Philip Doganis"
    }
  ], 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.5281/zenodo.3610182", 
  "@id": "https://doi.org/10.5281/zenodo.3610182", 
  "@type": "CreativeWork", 
  "name": "Jaqpot 5: How to simulate biodistribution scenarios using custom PBPK models"
}
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