Journal article Open Access

"DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF DALFAMPRIDINE, IN BULK AND PHARMACEUTICAL DOSAGE FORM."

Rathod K.G.


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{
  "description": "<p>A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Dalfampridine in its pure form as well as in tablet dosage form.&nbsp; Chromatography was carried out on ODS C18 (4.6 x 250mm, 5&micro;m) column using Acetonitrile and water in the ratio of 80:20 v/v,as the mobile phase at a flow rate of 1.0mL/min, The retention time obtained for DFP was 2.98 min. The method produce linear responses in the concentration range of 20 &micro;g/ml of&nbsp; Dalfampridine . The method precision for the determination of assay was below 2.0%RSD. The method is useful in the quality control of bulk and pharmaceutical formulations.</p>", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "creator": [
    {
      "affiliation": "Mangaldeep Institute of Pharmacy, Nipani, Aurangabad.", 
      "@type": "Person", 
      "name": "Rathod K.G."
    }
  ], 
  "headline": "\"DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF DALFAMPRIDINE, IN BULK AND PHARMACEUTICAL DOSAGE FORM.\"", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "datePublished": "2020-01-03", 
  "url": "https://zenodo.org/record/3597164", 
  "keywords": [
    "Dalfampridine; RP-HPLC; PDA Detection; Validation; Tablet Dosage Forms."
  ], 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.5281/zenodo.3597164", 
  "@id": "https://doi.org/10.5281/zenodo.3597164", 
  "@type": "ScholarlyArticle", 
  "name": "\"DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF DALFAMPRIDINE, IN BULK AND PHARMACEUTICAL DOSAGE FORM.\""
}
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