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Mass spectrometry analysis of contaminating band in HTT samples 2019/10/31

Harding, Rachel; Ackloo, Suzanne; Arrowsmith, Cheryl; Edwards, Aled


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    <dct:title>Mass spectrometry analysis of contaminating band in HTT samples 2019/10/31</dct:title>
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    <dcat:keyword>huntingtin</dcat:keyword>
    <dcat:keyword>Huntington's disease</dcat:keyword>
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    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2019-10-31</dct:issued>
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    <dct:description>&lt;p&gt;&lt;strong&gt;Project:&amp;nbsp;&lt;/strong&gt;Biophysical investigation of purified HTT protein samples&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Experiment:&amp;nbsp;&lt;/strong&gt;Mass spectrometry analysis of contaminating band in HTT samples&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Date completed:&amp;shy;&amp;nbsp;&lt;/strong&gt;2019/10/31&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Rationale:&amp;nbsp;&lt;/strong&gt;To determine the identity of ~100 kDa band seen on SDS-PAGE in HTT preps &amp;ndash; see&amp;nbsp;&lt;a href="https://zenodo.org/record/3555378"&gt;https://zenodo.org/record/3555378&lt;/a&gt;&lt;/p&gt;</dct:description>
    <dct:description>Dr. Harding is the recipient of the Huntington's Disease Society of America Berman Topper Career Development Fellowship which funds and supports this research, in addition to generous funding from the CHDI Foundation and the Huntington Society of Canada. The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.</dct:description>
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