September 22, 2017 Journal article Open Access

lF.Saladino; E.Posarelli; C.Luz; F.B.Luciano; M.T.Rodriguez-Estrada; J.Mañes; G.Meca

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{
  "description": "<p>Aflatoxins (AFs) are produced mainly by the molds Aspergillus flavus and Aspergillus parasiticus. Aflatoxin<br>\nB1 (AFB1) is classified as carcinogenic to humans. The aim of this study was to evaluate the capacity of<br>\ndifferent strains of Lactobacilli (Lb.) and Bifidobacteria (Bf.) to reduce the bioaccessibility of AFB1 and<br>\naflatoxin B2 (AFB2), spiked in loaf bread, using a dynamic in vitro simulated gastrointestinal digestion<br>\nsystem. Aliquots of 20 mL of gastric and duodenal fluids were sampled for the determination of the<br>\nmycotoxins gastric and duodenal bioaccessibility respectively, by liquid-chromatography coupled to the<br>\nmass spectrometry in tandem (LC&ndash;MS/MS). A reduction of AFs bioaccessibility compared to the control<br>\n(digestion without bacterial strains) was evidenced. The strains that evidenced the highest gastric and<br>\nduodenal bioaccessibility reductions of AFB1 and AFB2 were Lb. johnsoni CECT 289, Lb. reuteri CECT 725,<br>\nLb. plantarum CECT 220 and Lb. casei CECT 4180, with values ranging from 76.38 to 98.34% for AFB1 and<br>\nfrom 77.14 to 98.66% for AFB2. These results suggest that a food enriched with specific probiotic<br>\nmicroorganisms and consumed at the same time as food contaminated with AFs, could reduce the risk<br>\nassociated to the intake of these toxic compounds contained in food.</p>", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "creator": [
    {
      "@type": "Person", 
      "name": "lF.Saladino"
    }, 
    {
      "@type": "Person", 
      "name": "E.Posarelli"
    }, 
    {
      "@type": "Person", 
      "name": "C.Luz"
    }, 
    {
      "@type": "Person", 
      "name": "F.B.Luciano"
    }, 
    {
      "@type": "Person", 
      "name": "M.T.Rodriguez-Estrada"
    }, 
    {
      "@type": "Person", 
      "name": "J.Ma\u00f1es"
    }, 
    {
      "@type": "Person", 
      "name": "G.Meca"
    }
  ], 
  "headline": "Influence of probiotic microorganisms on aflatoxins B1 and B2 bioaccessibility evaluated with a simulated gastrointestinal digestion", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "datePublished": "2017-09-22", 
  "url": "https://zenodo.org/record/3531534", 
  "keywords": [
    "Aflatoxins Bioaccessibility Probiotic bacteria Lactobacillus Bifidobacterium"
  ], 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.1016/j.jfca.2017.01.010", 
  "@id": "https://doi.org/10.1016/j.jfca.2017.01.010", 
  "@type": "ScholarlyArticle", 
  "name": "Influence of probiotic microorganisms on aflatoxins B1 and B2 bioaccessibility evaluated with a simulated gastrointestinal digestion"
}