Journal article Open Access

Influence of probiotic microorganisms on aflatoxins B1 and B2 bioaccessibility evaluated with a simulated gastrointestinal digestion

lF.Saladino; E.Posarelli; C.Luz; F.B.Luciano; M.T.Rodriguez-Estrada; J.Mañes; G.Meca

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  <identifier identifierType="URL"></identifier>
    <title>Influence of probiotic microorganisms on aflatoxins B1 and B2 bioaccessibility evaluated with a simulated gastrointestinal digestion</title>
    <subject>Aflatoxins Bioaccessibility Probiotic bacteria Lactobacillus Bifidobacterium</subject>
    <date dateType="Issued">2017-09-22</date>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
    <alternateIdentifier alternateIdentifierType="url"></alternateIdentifier>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.jfca.2017.01.010</relatedIdentifier>
    <rights rightsURI="">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
    <description descriptionType="Abstract">&lt;p&gt;Aflatoxins (AFs) are produced mainly by the molds Aspergillus flavus and Aspergillus parasiticus. Aflatoxin&lt;br&gt;
B1 (AFB1) is classified as carcinogenic to humans. The aim of this study was to evaluate the capacity of&lt;br&gt;
different strains of Lactobacilli (Lb.) and Bifidobacteria (Bf.) to reduce the bioaccessibility of AFB1 and&lt;br&gt;
aflatoxin B2 (AFB2), spiked in loaf bread, using a dynamic in vitro simulated gastrointestinal digestion&lt;br&gt;
system. Aliquots of 20 mL of gastric and duodenal fluids were sampled for the determination of the&lt;br&gt;
mycotoxins gastric and duodenal bioaccessibility respectively, by liquid-chromatography coupled to the&lt;br&gt;
mass spectrometry in tandem (LC&amp;ndash;MS/MS). A reduction of AFs bioaccessibility compared to the control&lt;br&gt;
(digestion without bacterial strains) was evidenced. The strains that evidenced the highest gastric and&lt;br&gt;
duodenal bioaccessibility reductions of AFB1 and AFB2 were Lb. johnsoni CECT 289, Lb. reuteri CECT 725,&lt;br&gt;
Lb. plantarum CECT 220 and Lb. casei CECT 4180, with values ranging from 76.38 to 98.34% for AFB1 and&lt;br&gt;
from 77.14 to 98.66% for AFB2. These results suggest that a food enriched with specific probiotic&lt;br&gt;
microorganisms and consumed at the same time as food contaminated with AFs, could reduce the risk&lt;br&gt;
associated to the intake of these toxic compounds contained in food.&lt;/p&gt;</description>
      <funderName>European Commission</funderName>
      <funderIdentifier funderIdentifierType="Crossref Funder ID">10.13039/501100000780</funderIdentifier>
      <awardNumber awardURI="info:eu-repo/grantAgreement/EC/H2020/678781/">678781</awardNumber>
      <awardTitle>Integrated and innovative key actions for mycotoxin management in the food and feed chain</awardTitle>
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