An Investigation on the Anti-allergic Impacts of the Native Probiotic Bacteria Isolated from the Honey Crop of Asian Honey Bees on Allergic Mice Model

Probiotic bacteria exert positive effects on human health. Among a wide range of health beneficial effects, the anti-allergic effect is an important one. One indication of allergic reaction is the increase in IgE level in our body. The mechanism initialized by probiotic bacteria leads to the decrease of IgE level that ultimately inhibits the allergic reactions. The present study is aimed to screen anti-allergic effect of native probiotics isolated from nectar. The probiotic bacteria were isolated from the nectar sample collected from Rangpur district of Bangladesh. The isolated probiotic bacteria were then subjected to morphological and biochemical tests. These morphological and biochemical tests allowed us to ensure that the isolated bacteria were the probiotic type. Then animal trial was conducted using these probiotic isolates. In the study, mice were used as the animal model. At the end of the trial, the blood samples isolated from different mice groups were analyzed. It has been found that, the probiotic isolates had significant effect (p<0.05) on the IgE level of the mice used this experiment. IgE levels of treatment group 1, treatment group 2 and treatment group 3 were found (9.76±0.2 IU/ml), (5.69±0.14 IU/ml) and (3.22±0.11 IU/ml), respectively. While the probiotic isolates had no significant effect (p>0.05) on the eosinophil count and peripheral lymphocyte count of the mice used the experiment.