Dataset Open Access

ROS-Specific Huntingtin Interactions: Huntingtin chromatin retention dynamics by FRAP with veliparib

Maiuri, Tamara; Truant, Ray


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{
  "inLanguage": {
    "alternateName": "eng", 
    "@type": "Language", 
    "name": "English"
  }, 
  "description": "<p>Measurement of&nbsp;huntingtin chromatin recruitment dynamics by fluorescence recovery after photobleaching (FRAP) of the YFP-tagged huntingtin-specific intrabody, nucHCB2, under conditions of oxidative stress and PARP inhibition</p>", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "creator": [
    {
      "affiliation": "McMaster University", 
      "@id": "https://orcid.org/0000-0002-6103-5835", 
      "@type": "Person", 
      "name": "Maiuri, Tamara"
    }, 
    {
      "affiliation": "McMaster University", 
      "@id": "https://orcid.org/0000-0003-2542-6641", 
      "@type": "Person", 
      "name": "Truant, Ray"
    }
  ], 
  "url": "https://zenodo.org/record/3338633", 
  "datePublished": "2019-07-16", 
  "keywords": [
    "huntingtin", 
    "Huntington's disease", 
    "ROS", 
    "reactive oxygen species", 
    "oxidative stress", 
    "poly ADP ribose", 
    "PARP", 
    "RPE1", 
    "DNA repair", 
    "intrabody", 
    "FRAP", 
    "veliparib"
  ], 
  "@context": "https://schema.org/", 
  "distribution": [
    {
      "contentUrl": "https://zenodo.org/api/files/ea02b223-ed19-41cc-805d-7825441cf12d/2019-05-01 Huntingtin FRAP with veliparib.docx", 
      "encodingFormat": "docx", 
      "@type": "DataDownload"
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  ], 
  "identifier": "https://doi.org/10.5281/zenodo.3338633", 
  "@id": "https://doi.org/10.5281/zenodo.3338633", 
  "@type": "Dataset", 
  "name": "ROS-Specific Huntingtin Interactions: Huntingtin chromatin retention dynamics by FRAP with veliparib"
}
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