# WARNING: this file is not sorted! # db id alt E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 MA0003.3 TFAP2A 4.5e0000 8.6e-003 -4.76 0.0 264 490 687 1150 0.53878 3.5e-005 244 1 MA0027.2 EN1 2.2e-001 4.3e-004 -7.76 0.0 93 493 313 1299 0.18864 1.7e-006 246 1 MA0031.1 FOXD1 6.7e-025 1.3e-027 -61.92 0.0 43 493 250 1339 0.08722 5.2e-030 246 1 MA0032.2 FOXC1 6.7e-002 1.3e-004 -8.96 0.0 60 490 214 1258 0.12245 5.3e-007 244 1 MA0033.2 FOXL1 1.6e-037 3.1e-040 -90.96 0.0 62 494 349 1315 0.12551 1.3e-042 246 1 MA0036.2 GATA2 5.6e-002 1.1e-004 -9.13 0.0 123 487 232 688 0.25257 4.4e-007 243 1 MA0042.2 FOXI1 9.0e-025 1.7e-027 -61.62 0.0 62 494 302 1239 0.12551 7.1e-030 246 1 MA0047.2 Foxa2 4.5e0000 8.6e-003 -4.75 0.0 29 489 97 1074 0.05930 3.5e-005 244 1 MA0048.2 NHLH1 1.0e-001 2.0e-004 -8.51 0.0 179 491 424 963 0.36456 8.2e-007 245 1 MA0052.3 MEF2A 5.3e-639 1.0e-641 -1475.94 0.0 65 489 1048 1323 0.13292 4.2e-644 244 1 MA0063.1 Nkx2-5 2.0e-005 3.9e-008 -17.05 0.0 36 494 178 1492 0.07287 1.6e-010 246 1 MA0068.2 PAX4 2.3e-007 4.4e-010 -21.55 0.0 155 493 506 1237 0.31440 1.8e-012 246 1 MA0071.1 RORA 2.9e-001 5.6e-004 -7.48 0.0 125 491 211 625 0.25458 2.3e-006 245 1 MA0072.1 RORA(var.2) 7.1e-016 1.4e-018 -41.13 0.0 123 487 162 328 0.25257 5.6e-021 243 1 MA0075.2 Prrx2 1.2e-004 2.2e-007 -15.31 0.0 93 493 373 1475 0.18864 9.1e-010 246 1 MA0108.2 TBP 1.0e-156 2.0e-159 -365.42 0.0 60 486 587 1439 0.12346 8.2e-162 242 1 MA0117.2 Mafb 2.5e-002 4.7e-005 -9.96 0.0 183 489 590 1332 0.37423 1.9e-007 244 1 MA0125.1 Nobox 3.6e-020 6.9e-023 -51.03 0.0 69 493 328 1327 0.13996 2.8e-025 246 1 MA0132.2 PDX1 3.9e-003 7.5e-006 -11.81 0.0 65 493 222 1175 0.13185 3.0e-008 246 1 MA0140.2 GATA1::TAL1 8.0e0000 1.5e-002 -4.18 0.0 169 483 255 598 0.34990 6.4e-005 241 1 MA0148.3 FOXA1 2.0e0000 3.9e-003 -5.56 0.0 34 486 93 849 0.06996 1.6e-005 242 1 MA0151.1 Arid3a 1.2e0000 2.3e-003 -6.07 0.0 29 495 115 1298 0.05859 9.4e-006 247 1 MA0465.1 CDX2 2.1e-021 4.0e-024 -53.87 0.0 46 490 131 511 0.09388 1.7e-026 244 1 MA0467.1 Crx 3.4e-088 6.5e-091 -207.66 0.0 138 490 689 1226 0.28163 2.7e-093 244 1 MA0468.1 DUX4 9.5e0000 1.8e-002 -4.00 0.0 176 490 200 447 0.35918 7.6e-005 244 1 MA0472.2 EGR2 8.7e0000 1.7e-002 -4.09 0.0 444 490 421 440 0.90612 6.9e-005 244 1 MA0485.1 Hoxc9 5.8e-014 1.1e-016 -36.72 0.0 60 488 209 912 0.12295 4.6e-019 243 1 MA0492.1 JUND(var.2) 3.4e0000 6.5e-003 -5.04 0.0 50 486 62 355 0.10288 2.7e-005 242 1 MA0494.1 Nr1h3::Rxra 2.5e-001 4.7e-004 -7.66 0.0 16 482 67 1092 0.03320 2.0e-006 240 1 MA0495.1 MAFF 1.4e-001 2.7e-004 -8.22 0.0 249 483 643 1095 0.51553 1.1e-006 241 1 MA0497.1 MEF2C 7.4e-724 1.4e-726 -1671.32 0.0 60 486 1190 1568 0.12346 5.9e-729 242 1 MA0499.1 Myod1 4.5e-003 8.7e-006 -11.66 0.0 176 488 386 856 0.36066 3.6e-008 243 1 MA0500.1 Myog 5.2e-004 1.0e-006 -13.82 0.0 156 490 320 765 0.31837 4.1e-009 244 1 MA0506.1 NRF1 3.5e0000 6.8e-003 -4.99 0.0 398 490 399 451 0.81224 2.8e-005 244 1 MA0521.1 Tcf12 2.8e-006 5.3e-009 -19.05 0.0 186 490 413 838 0.37959 2.2e-011 244 1 MA0593.1 FOXP2 1.3e0000 2.5e-003 -5.98 0.0 32 490 80 743 0.06531 1.0e-005 244 1 MA0594.1 Hoxa9 2.0e0000 3.9e-003 -5.54 0.0 60 490 148 862 0.12245 1.6e-005 244 1 MA0601.1 Arid3b 2.1e-015 4.0e-018 -40.06 0.0 36 490 198 1338 0.07347 1.6e-020 244 1 MA0602.1 Arid5a 7.1e-014 1.4e-016 -36.53 0.0 25 487 136 1145 0.05133 5.6e-019 243 1 MA0607.1 Bhlha15 2.1e-002 4.1e-005 -10.10 0.0 193 493 359 740 0.39148 1.7e-007 246 1 MA0611.1 Dux 3.1e-002 6.1e-005 -9.71 0.0 267 493 366 565 0.54158 2.5e-007 246 1 MA0612.1 EMX1 1.1e-007 2.1e-010 -22.27 0.0 93 491 376 1410 0.18941 8.7e-013 245 1 MA0614.1 Foxj2 1.5e-005 2.9e-008 -17.37 0.0 57 493 216 1213 0.11562 1.2e-010 246 1 MA0618.1 LBX1 6.1e-010 1.2e-012 -27.47 0.0 57 493 232 1197 0.11562 4.8e-015 246 1 MA0621.1 mix-a 1.7e-001 3.2e-004 -8.04 0.0 68 490 146 715 0.13878 1.3e-006 244 1 MA0628.1 POU6F1 8.7e-002 1.7e-004 -8.69 0.0 67 491 188 976 0.13646 6.9e-007 245 1 MA0629.1 Rhox11 2.3e-030 4.4e-033 -74.50 0.0 48 484 263 1181 0.09917 1.8e-035 241 1 MA0630.1 SHOX 2.4e-006 4.6e-009 -19.20 0.0 93 493 372 1429 0.18864 1.9e-011 246 1 MA0634.1 ALX3 2.0e-008 3.9e-011 -23.97 0.0 69 491 303 1430 0.14053 1.6e-013 245 1 MA0635.1 BARHL2 6.1e-010 1.2e-012 -27.47 0.0 87 491 378 1460 0.17719 4.8e-015 245 1 MA0642.1 EN2 1.6e-002 3.1e-005 -10.37 0.0 105 491 381 1397 0.21385 1.3e-007 245 1 MA0644.1 ESX1 6.8e-006 1.3e-008 -18.15 0.0 93 491 379 1464 0.18941 5.4e-011 245 1 MA0648.1 GSC 1.5e-073 2.9e-076 -173.94 0.0 149 491 769 1413 0.30346 1.2e-078 245 1 MA0650.1 HOXA13 1.4e-014 2.8e-017 -38.13 0.0 49 491 235 1284 0.09980 1.1e-019 245 1 MA0654.1 ISX 1.4e-002 2.6e-005 -10.54 0.0 53 493 165 1019 0.10751 1.1e-007 246 1 MA0658.1 LHX6 5.1e-005 9.9e-008 -16.13 0.0 93 491 254 932 0.18941 4.0e-010 245 1 MA0660.1 MEF2B 8.8e-622 1.7e-624 -1436.28 0.0 77 489 1028 1199 0.15746 7.0e-627 244 1 MA0661.1 MEOX1 7.3e-003 1.4e-005 -11.17 0.0 183 491 549 1228 0.37271 5.7e-008 245 1 MA0662.1 MIXL1 2.6e-005 4.9e-008 -16.82 0.0 93 491 369 1436 0.18941 2.0e-010 245 1 MA0665.1 MSC 2.5e-001 4.7e-004 -7.65 0.0 93 491 222 874 0.18941 1.9e-006 245 1 MA0666.1 MSX1 5.3e0000 1.0e-002 -4.59 0.0 93 493 323 1397 0.18864 4.2e-005 246 1 MA0674.1 NKX6-1 5.1e-005 9.7e-008 -16.14 0.0 65 493 258 1342 0.13185 4.0e-010 246 1 MA0675.1 NKX6-2 2.3e-002 4.5e-005 -10.00 0.0 65 493 259 1442 0.13185 1.8e-007 246 1 MA0681.1 Phox2b 7.2e-010 1.4e-012 -27.31 0.0 88 490 264 932 0.17959 5.7e-015 244 1 MA0682.1 Pitx1 1.3e-081 2.6e-084 -192.47 0.0 121 493 736 1540 0.24544 1.0e-086 246 1 MA0691.1 TFAP4 3.7e-001 7.1e-004 -7.26 0.0 219 491 353 660 0.44603 2.9e-006 245 1 MA0699.1 LBX2 8.0e-003 1.6e-005 -11.07 0.0 73 491 292 1455 0.14868 6.3e-008 245 1 MA0700.1 LHX2 7.8e-003 1.5e-005 -11.11 0.0 67 491 206 1052 0.13646 6.1e-008 245 1 MA0701.1 LHX9 5.9e-001 1.1e-003 -6.78 0.0 61 493 240 1467 0.12373 4.6e-006 246 1 MA0702.1 LMX1A 4.3e-002 8.2e-005 -9.41 0.0 71 493 257 1322 0.14402 3.3e-007 246 1 MA0703.1 LMX1B 6.2e-008 1.2e-010 -22.84 0.0 65 493 294 1479 0.13185 4.9e-013 246 1 MA0704.1 Lhx4 3.1e-007 6.0e-010 -21.23 0.0 69 493 292 1401 0.13996 2.4e-012 246 1 MA0705.1 Lhx8 7.8e-003 1.5e-005 -11.10 0.0 93 493 276 1086 0.18864 6.1e-008 246 1 MA0706.1 MEOX2 5.4e-002 1.0e-004 -9.17 0.0 93 491 349 1439 0.18941 4.3e-007 245 1 MA0707.1 MNX1 2.0e-005 3.9e-008 -17.07 0.0 23 491 122 1412 0.04684 1.6e-010 245 1 MA0708.1 MSX2 2.3e-005 4.4e-008 -16.94 0.0 67 493 259 1300 0.13590 1.8e-010 246 1 MA0709.1 Msx3 3.6e-004 7.0e-007 -14.18 0.0 93 493 323 1261 0.18864 2.8e-009 246 1 MA0710.1 NOTO 8.7e-002 1.7e-004 -8.69 0.0 25 491 109 1306 0.05092 6.9e-007 245 1 MA0711.1 OTX1 6.9e-098 1.3e-100 -229.97 0.0 133 493 759 1396 0.26978 5.4e-103 246 1 MA0712.1 OTX2 2.5e-088 4.9e-091 -207.95 0.0 149 493 822 1466 0.30223 2.0e-093 246 1 MA0713.1 PHOX2A 6.8e-010 1.3e-012 -27.35 0.0 88 490 297 1075 0.17959 5.4e-015 244 1 MA0714.1 PITX3 1.2e-082 2.3e-085 -194.87 0.0 118 492 719 1513 0.23984 9.5e-088 245 1 MA0716.1 PRRX1 6.8e-004 1.3e-006 -13.55 0.0 93 493 356 1421 0.18864 5.3e-009 246 1 MA0717.1 RAX2 2.1e-006 4.1e-009 -19.31 0.0 93 493 379 1457 0.18864 1.7e-011 246 1 MA0718.1 RAX 2.3e-007 4.4e-010 -21.54 0.0 65 491 270 1340 0.13238 1.8e-012 245 1 MA0719.1 RHOXF1 6.9e-046 1.3e-048 -110.24 0.0 117 493 651 1598 0.23732 5.4e-051 246 1 MA0720.1 Shox2 3.2e-004 6.2e-007 -14.30 0.0 93 493 340 1339 0.18864 2.5e-009 246 1 MA0721.1 UNCX 3.0e-004 5.8e-007 -14.36 0.0 99 493 383 1443 0.20081 2.4e-009 246 1 MA0722.1 VAX1 4.0e-013 7.7e-016 -34.80 0.0 67 493 323 1477 0.13590 3.1e-018 246 1 MA0723.1 VAX2 7.0e-005 1.4e-007 -15.82 0.0 67 493 283 1458 0.13590 5.5e-010 246 1 MA0724.1 VENTX 6.5e-006 1.3e-008 -18.20 0.0 88 492 278 1075 0.17886 5.1e-011 245 1 MA0725.1 VSX1 3.3e-008 6.3e-011 -23.49 0.0 67 493 283 1361 0.13590 2.6e-013 246 1 MA0726.1 VSX2 9.9e-008 1.9e-010 -22.38 0.0 67 493 269 1294 0.13590 7.8e-013 246 1 MA0766.1 GATA5 6.3e-007 1.2e-009 -20.53 0.0 109 493 432 1446 0.22110 4.9e-012 246 1 MA0773.1 MEF2D 4.4e-604 8.5e-607 -1395.53 0.0 77 489 1006 1179 0.15746 3.5e-609 244 1 MA0788.1 POU3F3 1.0e0000 1.9e-003 -6.25 0.0 20 488 74 1054 0.04098 7.9e-006 243 1 MA0792.1 POU5F1B 4.1e-001 7.8e-004 -7.15 0.0 36 492 142 1310 0.07317 3.2e-006 245 1 MA0793.1 POU6F2 2.4e-020 4.6e-023 -51.42 0.0 65 491 278 1121 0.13238 1.9e-025 245 1 MA0814.1 TFAP2C(var.2) 5.7e-001 1.1e-003 -6.81 0.0 414 490 984 1103 0.84490 4.5e-006 244 1 MA0816.1 Ascl2 1.2e-007 2.4e-010 -22.15 0.0 143 491 474 1229 0.29124 9.8e-013 245 1 MA0818.1 BHLHE22 2.0e0000 3.8e-003 -5.56 0.0 141 491 203 548 0.28717 1.6e-005 245 1 MA0826.1 OLIG1 5.3e0000 1.0e-002 -4.58 0.0 173 491 168 371 0.35234 4.2e-005 245 1 MA0832.1 Tcf21 5.9e-001 1.1e-003 -6.78 0.0 265 487 174 255 0.54415 4.7e-006 243 1 MA0842.1 NRL 7.9e-002 1.5e-004 -8.80 0.0 100 490 403 1579 0.20408 6.2e-007 244 1 MA0845.1 FOXB1 8.2e-006 1.6e-008 -17.96 0.0 38 490 156 1172 0.07755 6.5e-011 244 1 MA0847.1 FOXD2 5.2e-044 1.0e-046 -105.91 0.0 56 494 382 1542 0.11336 4.1e-049 246 1 MA0848.1 FOXO4 1.0e-015 2.0e-018 -40.75 0.0 32 494 189 1408 0.06478 8.2e-021 246 1 MA0849.1 FOXO6 1.3e-015 2.4e-018 -40.57 0.0 32 494 171 1224 0.06478 9.8e-021 246 1 MA0850.1 FOXP3 2.8e-006 5.4e-009 -19.04 0.0 50 494 241 1548 0.10121 2.2e-011 246 1 MA0851.1 Foxj3 6.5e-007 1.3e-009 -20.49 0.0 32 484 131 1048 0.06612 5.2e-012 241 1 MA0853.1 Alx4 2.0e-004 3.8e-007 -14.77 0.0 68 484 148 650 0.14050 1.6e-009 241 1 MA0854.1 Alx1 7.4e-008 1.4e-010 -22.68 0.0 76 484 175 657 0.15702 5.9e-013 241 1 MA0874.1 Arx 7.5e-002 1.5e-004 -8.84 0.0 66 484 110 509 0.13636 6.0e-007 241 1 MA0875.1 BARX1 1.1e-009 2.2e-012 -26.84 0.0 79 493 340 1420 0.16024 9.0e-015 246 1 MA0876.1 BSX 8.7e-007 1.7e-009 -20.21 0.0 79 493 318 1375 0.16024 6.8e-012 246 1 MA0877.1 Barhl1 8.3e-009 1.6e-011 -24.85 0.0 77 491 357 1559 0.15682 6.6e-014 245 1 MA0878.1 CDX1 4.5e-028 8.6e-031 -69.23 0.0 50 492 295 1400 0.10163 3.5e-033 245 1 MA0879.1 Dlx1 1.1e-065 2.0e-068 -155.87 0.0 41 491 357 1527 0.08350 8.3e-071 245 1 MA0880.1 Dlx3 5.8e-006 1.1e-008 -18.30 0.0 71 493 305 1473 0.14402 4.6e-011 246 1 MA0881.1 Dlx4 1.1e-011 2.1e-014 -31.51 0.0 67 493 320 1493 0.13590 8.4e-017 246 1 MA0882.1 DLX6 2.8e-007 5.4e-010 -21.34 0.0 67 493 287 1410 0.13590 2.2e-012 246 1 MA0883.1 Dmbx1 3.4e-092 6.5e-095 -216.87 0.0 132 484 625 1084 0.27273 2.7e-097 241 1 MA0884.1 DUXA 5.6e-008 1.1e-010 -22.96 0.0 144 488 399 991 0.29508 4.4e-013 243 1 MA0885.1 Dlx2 8.2e-005 1.6e-007 -15.66 0.0 73 493 292 1395 0.14807 6.4e-010 246 1 MA0886.1 EMX2 9.7e-004 1.9e-006 -13.19 0.0 83 491 270 1150 0.16904 7.6e-009 245 1 MA0887.1 EVX1 8.3e-019 1.6e-021 -47.88 0.0 93 491 426 1418 0.18941 6.5e-024 245 1 MA0888.1 EVX2 1.3e-016 2.5e-019 -42.85 0.0 83 491 385 1424 0.16904 1.0e-021 245 1 MA0889.1 GBX1 2.6e-003 5.0e-006 -12.20 0.0 93 491 252 959 0.18941 2.0e-008 245 1 MA0890.1 GBX2 2.3e-001 4.4e-004 -7.72 0.0 93 491 287 1173 0.18941 1.8e-006 245 1 MA0891.1 GSC2 4.2e-075 8.0e-078 -177.52 0.0 149 491 822 1531 0.30346 3.3e-080 245 1 MA0892.1 GSX1 8.7e-012 1.7e-014 -31.72 0.0 93 491 419 1509 0.18941 6.8e-017 245 1 MA0893.1 GSX2 2.6e-015 5.0e-018 -39.84 0.0 71 491 355 1516 0.14460 2.0e-020 245 1 MA0894.1 HESX1 1.2e-001 2.3e-004 -8.38 0.0 93 491 252 1002 0.18941 9.4e-007 245 1 MA0896.1 Hmx1 1.4e0000 2.8e-003 -5.88 0.0 116 484 246 803 0.23967 1.2e-005 241 1 MA0899.1 HOXA10 1.6e-025 3.1e-028 -63.33 0.0 36 490 238 1457 0.07347 1.3e-030 244 1 MA0900.1 HOXA2 4.0e-003 7.8e-006 -11.77 0.0 97 491 371 1445 0.19756 3.2e-008 245 1 MA0901.1 HOXB13 3.0e-022 5.7e-025 -55.82 0.0 47 491 243 1225 0.09572 2.3e-027 245 1 MA0902.1 HOXB2 2.4e-004 4.5e-007 -14.60 0.0 65 491 275 1463 0.13238 1.9e-009 245 1 MA0903.1 HOXB3 2.9e-008 5.6e-011 -23.61 0.0 65 491 295 1467 0.13238 2.3e-013 245 1 MA0904.1 Hoxb5 5.6e-006 1.1e-008 -18.35 0.0 69 485 199 889 0.14227 4.4e-011 242 1 MA0905.1 HOXC10 1.3e0000 2.4e-003 -6.03 0.0 41 491 124 1004 0.08350 9.9e-006 245 1 MA0909.1 HOXD13 9.6e-009 1.9e-011 -24.71 0.0 51 491 203 1151 0.10387 7.6e-014 245 1 MA0910.1 Hoxd8 6.4e-053 1.2e-055 -126.43 0.0 46 484 300 1158 0.09504 5.1e-058 241 1 MA0911.1 Hoxa11 3.9e0000 7.5e-003 -4.90 0.0 45 489 119 891 0.09202 3.1e-005 244 1 MA0912.1 Hoxd3 1.1e-001 2.1e-004 -8.49 0.0 67 485 204 1065 0.13814 8.5e-007 242 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # E-value: The expected number motifs that would have least one # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).