ISOLATION AND CHARACTERIZATION OF BINDING AGENT FROM BLACK GRAM

ABSTRACT

Development of new excipients is time consuming involves tedious procedures and highly expensive. Instead, identification of new uses for the existing substances is relatively and less time consuming. The intention of present study was designed for isolation and characterization of binding agent from the seeds of Vigna mungo (Black gram seeds) and explores its use as pharmaceutical excipients. Binding agent was isolated by using two different methods. The isolated binding agent (powder) was investigated for purity by carrying out chemical tests for different Phytochemical constituents and only carbohydrates were found to be present. The binding agent (powder) was further characterized for physical and flow properties. Powder has good swelling index 60, PH 6.2, Melting point 137, Moisture absorption 2.45, Loss on drying 1.25. The binding agent (powder) had good flow property as Carr’s Index 17.30, Angle of repose 35.6 and Hausnor’s ratio 1.21. From the study, it indicates that Vigna mungo seeds (Black gram seeds) powder has satisfactory PH and physicochemical Properties, which can be used as pharmaceutical excipients in formulating various dosage form.

KEYWORDS: Excipients, Powder, Vigna mungo, Seeds, Methods.