3264828
doi
10.5281/zenodo.3264828
oai:zenodo.org:3264828
user-iajpr
REVIEW ON BIOMARKERS: TOOL FOR DIAGNOSIS OF A DISEASE AND DRUG DEVELOPMENT
Sandip S. Kshirsagar, Vaishali R. Shinde, Manjusha Nevase, Sayali Dudhal
Kasturi Shikshan Sanstha's College of Pharmacy, Shikrapur, Pune-412207, Maharashtra, India.
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Biomarker, Diagnostic Biomarkers, Surrogate Markers.
<p>Biomarker measurements have become an essential component of oncology drug development, particularly so in this era of targeted therapies. Such measurements ensure that clinical studies are testing our biological hypotheses and can help make the difficult decisions required to choose which drugs to stop developing or de-prioritise. In this review we discuss the intrinsic properties of biological sample based efficacy measurements and how these relate to their implementation in oncology drug development by way of points to consider and examples. In short use of biomarker data will help us make the best possible use of precious human samples and maximize the chances of success of the most promising therapeutic approaches.</p>
Zenodo
2019-06-30
info:eu-repo/semantics/article
3264827
user-iajpr
1579538575.499082
841072
md5:4acd3ee4330b598529b0cc7ec5af7885
https://zenodo.org/records/3264828/files/190520.pdf
public
10.5281/zenodo.3264827
isVersionOf
doi