Dataset Open Access

ROS-Specific Huntingtin Interactions: Chromatin Retention of Huntingtin in PARP KO Cells

Maiuri, Tamara; Truant, Ray


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  <identifier identifierType="DOI">10.5281/zenodo.3251038</identifier>
  <creators>
    <creator>
      <creatorName>Maiuri, Tamara</creatorName>
      <givenName>Tamara</givenName>
      <familyName>Maiuri</familyName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-6103-5835</nameIdentifier>
      <affiliation>McMaster University</affiliation>
    </creator>
    <creator>
      <creatorName>Truant, Ray</creatorName>
      <givenName>Ray</givenName>
      <familyName>Truant</familyName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0003-2542-6641</nameIdentifier>
      <affiliation>McMaster University</affiliation>
    </creator>
  </creators>
  <titles>
    <title>ROS-Specific Huntingtin Interactions: Chromatin Retention of Huntingtin in PARP KO Cells</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2019</publicationYear>
  <subjects>
    <subject>huntingtin</subject>
    <subject>Huntington's disease</subject>
    <subject>ROS</subject>
    <subject>reactive oxygen species</subject>
    <subject>oxidative stress</subject>
    <subject>chromatin retention assay</subject>
    <subject>PARP</subject>
    <subject>poly ADP ribose</subject>
    <subject>intrabody</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2019-06-20</date>
  </dates>
  <language>en</language>
  <resourceType resourceTypeGeneral="Dataset"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/3251038</alternateIdentifier>
  </alternateIdentifiers>
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    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/openlabnotebooks</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/truantlab</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;Huntingtin chromatin retention in response to oxidative stress in wild type, PARP1 knockout, PARP2 knockout, and PARP1/PARP2 knockout RPE1 cells.&lt;/p&gt;</description>
    <description descriptionType="Other">This work is funded by the HDSA Berman/Topper HD Career Development Fellowship.</description>
  </descriptions>
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