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Initiatives to Build a Whole-Cell Modeling Community: 2019 Update

Karr, Jonathan R; Lluch-Senar, Maria; Kastelic, Damjana; Serrano, Luis; Sauro, Herbert M

Whole-cell (WC) models that predict phenotype from genotype have the potential to transform biology, bioengineering, and medicine. Achieving WC models will likely require collaboration among modelers, experimentalists, mathematicians, computer scientists, and engineers. In 2012, we and others began to build a WC community by organizing a central website, a primer, schools, hackathons, and challenges. This year, we have continued to build a WC community by developing a new website, expanding the primer, organizing a third school, and launching an online seminar. Here, we summarize these initiatives, their impact to date, and our plans to continue to build a WC community.

These efforts were supported by National Science Foundation awards 1548123 and 1649014 to JRK, National Institutes of Health award R35 GM119771 to JRK, and National Institutes of Health award P41 EB023912 to Herbert Sauro. The 2019 school was also supported by an EMBO Practical Course award to JRK, MLS, and DK.
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