Dataset Open Access

Host-pathogen protein interactions predicted using structure

Davis, Fred


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    <dct:title>Host-pathogen protein interactions predicted using structure</dct:title>
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    <dcat:keyword>protein-protein interactions</dcat:keyword>
    <dcat:keyword>host-pathogen interactions</dcat:keyword>
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    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2015-08-26</dct:issued>
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    <dct:description>&lt;p&gt;This dataset accompanies a manuscript describing a method to predict host-pathogen protein interactions using structure:&lt;/p&gt; &lt;p&gt;Host-pathogen protein interactions predicted by comparative modeling.&lt;br /&gt; Davis FP, Barkan DT, Eswar N, McKerrow JH, Sali A. Protein Sci (2007) 16:2585-2596.&lt;br /&gt; http://www.proteinscience.org/cgi/doi/10.1110/ps.073228407&lt;/p&gt; &lt;p&gt;The files contain predictions made for 10 human pathogens including species of Mycobacterium, Apicomplexa, and Kinetoplastida. The species.all.zip files contain all interactions predictions for each species along with the filter criteria that each interaction passed. The species.filter.zip files contains the same information, but only for the subset of interactions that passed the biological and network-level filters. These files can be viewed in any spreadsheet program, such as Excel.&lt;/p&gt; &lt;p&gt;&amp;nbsp;&lt;/p&gt; &lt;p&gt;Predictions were made for interactions between human and&amp;nbsp;&lt;/p&gt; &lt;ol&gt; &lt;li&gt;Mycobacterium tuberculosis: mtuber&lt;/li&gt; &lt;li&gt;Mycobacterium leprae: mleprae&lt;/li&gt; &lt;li&gt;Leishmania major: lmajor&lt;/li&gt; &lt;li&gt;Trypanosoma brucei: tbrucei&lt;/li&gt; &lt;li&gt;Trypanosoma cruzi: tcruzi&lt;/li&gt; &lt;li&gt;Cryptosporidium hominis: chominis&lt;/li&gt; &lt;li&gt;Cryptosporidium parvum: cparvum&lt;/li&gt; &lt;li&gt;Plasmodium falciparum: pfalciparum&lt;/li&gt; &lt;li&gt;Plasmodium vivax: pvivax&lt;/li&gt; &lt;li&gt;Toxoplasma gondii: tgondi&lt;/li&gt; &lt;/ol&gt;</dct:description>
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