Journal article Open Access

ISCHEMIA MODIFIED ALBUMIN (IMA) IN SERUM AS A BIOCHEMICAL MARKER IN PRE-ECLAMPSIA

Dr. Navanil Roy, Dr. Mrinal Gupta*

BACKGROUND: Pre-eclampsia (PE) , a pregnancy specific disorder is the most common cause of foetal and maternal death. Yet no specific prevention and treatment is available. Ischemia Modified Albumin (IMA) has emerged as a marker in different diseases where ischemia is the origin or consequence behind disease pathology. Reliable biochemical markers for prediction and diagnosis of PE can have a better impact on maternal health and several of the markers have been suggested till now. MATERIALS & METHODS: 30 patients with PE were selected for the study and compared with 30 pregnant healthy controls. IMA were estimated in these patients. The results were then statistically analysed. RESULTS: IMA levels were found significantly raised in PE patients as compared to normal pregnant controls (p value<0.001). CONCLUSION: IMA which is generated by hypoxia/ischemia driven oxidative stress is also raised in PE and hence can be used as a biomarker in PE. Further studies are needed to establish the relationship between IMA and the disease process and its association with severity of disease.

Files (626.2 kB)
Name Size
190402.pdf
md5:5c062daf898032551c6999a985a4c346
626.2 kB Download
47
46
views
downloads
All versions This version
Views 4747
Downloads 4646
Data volume 28.8 MB28.8 MB
Unique views 4646
Unique downloads 4242

Share

Cite as