Journal article Open Access

Re-Purification of ALK2 for crystallisation with different compounds from M4K.

Williams, E.P.; Bullock, A.N.


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  <dc:creator>Williams, E.P.</dc:creator>
  <dc:creator>Bullock, A.N.</dc:creator>
  <dc:date>2019-04-24</dc:date>
  <dc:description>Cleaning up of a frozen purified sample of ALK2/ACVR1 by gel filtration after thawing for use in co-crystallisation trials with five M4K compounds (M4K2163, M4K2143, M4K2192, M4K2207 and M4K2194). You can read more about it on Open Lab Notebooks.</dc:description>
  <dc:description>Funding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.</dc:description>
  <dc:identifier>https://zenodo.org/record/2650203</dc:identifier>
  <dc:identifier>10.5281/zenodo.2650203</dc:identifier>
  <dc:identifier>oai:zenodo.org:2650203</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>doi:10.5281/zenodo.2650202</dc:relation>
  <dc:relation>url:https://zenodo.org/communities/openlabnotebooks</dc:relation>
  <dc:relation>url:https://zenodo.org/communities/sgc-opennotebook</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://creativecommons.org/licenses/by/4.0/legalcode</dc:rights>
  <dc:subject>ALK2</dc:subject>
  <dc:subject>ACVR1A</dc:subject>
  <dc:subject>Crystallisation</dc:subject>
  <dc:subject>M4K Pharma</dc:subject>
  <dc:title>Re-Purification of ALK2 for crystallisation with different compounds from M4K.</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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