Journal article Open Access

Re-Purification of ALK2 for crystallisation with different compounds from M4K.

Williams, E.P.; Bullock, A.N.


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  <identifier identifierType="DOI">10.5281/zenodo.2650203</identifier>
  <creators>
    <creator>
      <creatorName>Williams, E.P.</creatorName>
      <givenName>E.P.</givenName>
      <familyName>Williams</familyName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-1331-9518</nameIdentifier>
      <affiliation>Structural Genomics Consortium</affiliation>
    </creator>
    <creator>
      <creatorName>Bullock, A.N.</creatorName>
      <givenName>A.N.</givenName>
      <familyName>Bullock</familyName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0001-6757-0436</nameIdentifier>
      <affiliation>Structural Genomics Consortium</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Re-Purification of ALK2 for crystallisation with different compounds from M4K.</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2019</publicationYear>
  <subjects>
    <subject>ALK2</subject>
    <subject>ACVR1A</subject>
    <subject>Crystallisation</subject>
    <subject>M4K Pharma</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2019-04-24</date>
  </dates>
  <language>en</language>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/2650203</alternateIdentifier>
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    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.2650202</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/openlabnotebooks</relatedIdentifier>
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  <rightsList>
    <rights rightsURI="http://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;Cleaning up of a frozen purified sample of ALK2/ACVR1 by gel filtration after thawing for use in co-crystallisation trials with five M4K compounds (M4K2163, M4K2143, M4K2192, M4K2207 and M4K2194). You can read more about it on &lt;a href="https://openlabnotebooks.org/?p=2753&amp;amp;preview=true"&gt;Open Lab Notebooks&lt;/a&gt;.&lt;/p&gt;</description>
    <description descriptionType="Other">Funding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.</description>
  </descriptions>
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