Journal article Open Access

Re-Purification of ALK2 for crystallisation with different compounds from M4K.

Williams, E.P.; Bullock, A.N.


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    <dct:title>Re-Purification of ALK2 for crystallisation with different compounds from M4K.</dct:title>
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    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#gYear">2019</dct:issued>
    <dcat:keyword>ALK2</dcat:keyword>
    <dcat:keyword>ACVR1A</dcat:keyword>
    <dcat:keyword>Crystallisation</dcat:keyword>
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    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2019-04-24</dct:issued>
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    <dct:description>&lt;p&gt;Cleaning up of a frozen purified sample of ALK2/ACVR1 by gel filtration after thawing for use in co-crystallisation trials with five M4K compounds (M4K2163, M4K2143, M4K2192, M4K2207 and M4K2194). You can read more about it on &lt;a href="https://openlabnotebooks.org/?p=2753&amp;amp;preview=true"&gt;Open Lab Notebooks&lt;/a&gt;.&lt;/p&gt;</dct:description>
    <dct:description xml:lang="">Funding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.</dct:description>
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