2579323
doi
10.5281/zenodo.2579323
oai:zenodo.org:2579323
Desislav Dinev
Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Block 25, Sofia 1113, Bulgaria
Iva Gavrilova-Valchеva
University Specialized Hospital for Active Treatment in Oncology, Sofia, 6 Plovdivsko Pole Str., Sofia, Bulgaria
Ivan Gavrilov
University Specialized Hospital for Active Treatment in Oncology, Sofia, 6 Plovdivsko Pole Str., Sofia, Bulgaria
Cell cultures as model systems in breast cancer research
Radostina Alexandrova
Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Block 25, Sofia 1113, Bulgaria
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Primary cell cultures and immortal cell lines; 2D and 3D cell cultures, breast cancer
<p>Despite undoubted success in early diagnosis and treatment of breast cancer, it remains one of the most common and lethal neoplastic diseases in the world among women. Adequate model systems, including cell cultures, can help us better understand breast cancer biology as well as for the discovery of new diagnostic, prognostic and therapeutic strategies. This review summarizes some of the main characteristics of cell cultures (primary cell cultures and immortal cell lines; 2D and 3D cell cultures) used in current biomedical research and their strengths and weaknesses.</p>
Zenodo
2019-02-27
info:eu-repo/semantics/article
2579322
1579528041.096937
135106
md5:210d32489cc081cee5947be104e4da66
https://zenodo.org/records/2579323/files/Alexandrova et al.pdf
public
10.5281/zenodo.2579322
isVersionOf
doi