Journal article Open Access

Association between carotenoids and prostate cancer risk: A Meta-Analysis

Benkhadda Hadjer; Bouchentouf Manel; El Herrag Salah Eddine


MARC21 XML Export

<?xml version='1.0' encoding='UTF-8'?>
<record xmlns="http://www.loc.gov/MARC21/slim">
  <leader>00000nam##2200000uu#4500</leader>
  <datafield tag="041" ind1=" " ind2=" ">
    <subfield code="a">eng</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Prostate cancer</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Carotenoids</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Lycopene</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">β-Carotene</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">α-Carotene</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">β-cryptoxanthin</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Lutein/zeaxanthin</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Meta-analysis.</subfield>
  </datafield>
  <controlfield tag="005">20191114191001.0</controlfield>
  <controlfield tag="001">2575438</controlfield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, PO Box 89, Sidi-Bel-Abbes (22000), Algeria</subfield>
    <subfield code="a">Bouchentouf Manel</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, PO Box 89, Sidi-Bel-Abbes (22000), Algeria</subfield>
    <subfield code="a">El Herrag Salah Eddine</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">613488</subfield>
    <subfield code="z">md5:e03210e198ac0ee66a10083b3be82ef7</subfield>
    <subfield code="u">https://zenodo.org/record/2575438/files/Benkhedda et al. Vol 03 Issue 05.pdf</subfield>
  </datafield>
  <datafield tag="542" ind1=" " ind2=" ">
    <subfield code="l">open</subfield>
  </datafield>
  <datafield tag="260" ind1=" " ind2=" ">
    <subfield code="c">2019-02-17</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="O">
    <subfield code="o">oai:zenodo.org:2575438</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="4">
    <subfield code="c">131-139</subfield>
    <subfield code="n">05</subfield>
    <subfield code="p">The North African Journal of Food and Nutrition Research</subfield>
    <subfield code="v">03</subfield>
  </datafield>
  <datafield tag="100" ind1=" " ind2=" ">
    <subfield code="u">Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, PO Box 89, Sidi-Bel-Abbes (22000), Algeria</subfield>
    <subfield code="a">Benkhadda Hadjer</subfield>
  </datafield>
  <datafield tag="245" ind1=" " ind2=" ">
    <subfield code="a">Association between carotenoids and prostate cancer risk: A Meta-Analysis</subfield>
  </datafield>
  <datafield tag="540" ind1=" " ind2=" ">
    <subfield code="u">http://creativecommons.org/licenses/by/4.0/legalcode</subfield>
    <subfield code="a">Creative Commons Attribution 4.0 International</subfield>
  </datafield>
  <datafield tag="650" ind1="1" ind2="7">
    <subfield code="a">cc-by</subfield>
    <subfield code="2">opendefinition.org</subfield>
  </datafield>
  <datafield tag="520" ind1=" " ind2=" ">
    <subfield code="a">&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Carotenoids have been hypothesized to promote the prevention and treatment of prostate cancer (PC). &lt;strong&gt;Aims:&amp;nbsp;&lt;/strong&gt;Conducting a meta-analysis to assess whether the association differs by the type of carotenoids and to compare the relationships of each type of carotenoid with PC risk. &lt;strong&gt;Methods and Material: &lt;/strong&gt;&amp;nbsp;A literature search was conducted using the PubMed database. Pertinent studies were included in the meta-analysis of higher versus lower categories of dietary intakes or serum concentrations of carotenoids in relation to PC. A random-effects model was used to obtain the pooled odds ratios (ORs) and their confidence intervals (95%) of the case-control and cohort studies, for generic inverse variance data.&lt;strong&gt; Results: &lt;/strong&gt;13 identified studies involved 44,861 participants. The meta-analysis determined, for total carotenoids and lycopene, a statistically significant relationship with PC risk; OR: 0.88; 95% CI 0.81-0.96 and 0.87; 95% CI 0.77-0.99 respectively. However, no other carotenoid was noticed to have a statistically significant association with PC risk. Comparison of the effect of each type of carotenoid on PC risk showed that lycopene, lutein-zeaxanthin, and &amp;beta;-cryptoxanthin had a moderate inverse but not statistically significant relationship with PC risk. Compared to &amp;beta;-carotene, and &amp;alpha;-carotene results, their effect estimates were higher than the previous carotenoids. &lt;strong&gt;Conclusions: &lt;/strong&gt;&amp;nbsp;Our findings indicate that PC was inversely associated with total carotenoids and lycopene dietary intake and serum concentrations. These data provide support for the utilization of carotenoids for the treatment and prevention of PC.&lt;/p&gt;</subfield>
  </datafield>
  <datafield tag="773" ind1=" " ind2=" ">
    <subfield code="n">doi</subfield>
    <subfield code="i">isVersionOf</subfield>
    <subfield code="a">10.5281/zenodo.2567567</subfield>
  </datafield>
  <datafield tag="024" ind1=" " ind2=" ">
    <subfield code="a">10.5281/zenodo.2575438</subfield>
    <subfield code="2">doi</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">publication</subfield>
    <subfield code="b">article</subfield>
  </datafield>
</record>
110
58
views
downloads
All versions This version
Views 11098
Downloads 5853
Data volume 35.6 MB32.5 MB
Unique views 8982
Unique downloads 4945

Share

Cite as