Journal article Open Access

Recognizing taste: coding patterns along the neural axis in mammals

Ohla, Kathrin; Yoshida, Ryusuke; Roper, Steven D.; Di Lorenzo, Patricia M.; Victor, Jonathan D.; Boughter Jr., John D.; Fletcher, Max; Katz, Donald B.; Chaudhari. Nirupa


MARC21 XML Export

<?xml version='1.0' encoding='UTF-8'?>
<record xmlns="http://www.loc.gov/MARC21/slim">
  <leader>00000nam##2200000uu#4500</leader>
  <datafield tag="041" ind1=" " ind2=" ">
    <subfield code="a">eng</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">gustatory coding</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">taste quality</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">taste bud</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">geniculate ganglion</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">nucleus of solitary tract</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">gustatory cortex</subfield>
  </datafield>
  <controlfield tag="005">20200120171206.0</controlfield>
  <controlfield tag="001">2564740</controlfield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Okayama University</subfield>
    <subfield code="a">Yoshida, Ryusuke</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">University of Miami Miller School of Medicine</subfield>
    <subfield code="a">Roper, Steven D.</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Binghamton University</subfield>
    <subfield code="a">Di Lorenzo, Patricia M.</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Weill Cornell Medical College</subfield>
    <subfield code="a">Victor, Jonathan D.</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">University of Tennessee Health Science Center</subfield>
    <subfield code="a">Boughter Jr., John D.</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">University of Tennessee Health Science Center</subfield>
    <subfield code="a">Fletcher, Max</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">Brandeis University</subfield>
    <subfield code="a">Katz, Donald B.</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">University of Miami Miller School of Medicine</subfield>
    <subfield code="a">Chaudhari. Nirupa</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">638089</subfield>
    <subfield code="z">md5:661b9186d461e9bd58a6eb203f5e39e6</subfield>
    <subfield code="u">https://zenodo.org/record/2564740/files/Ohla et al_postprint.docx</subfield>
  </datafield>
  <datafield tag="542" ind1=" " ind2=" ">
    <subfield code="l">open</subfield>
  </datafield>
  <datafield tag="260" ind1=" " ind2=" ">
    <subfield code="c">2019-02-14</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="O">
    <subfield code="p">openaire</subfield>
    <subfield code="o">oai:zenodo.org:2564740</subfield>
  </datafield>
  <datafield tag="100" ind1=" " ind2=" ">
    <subfield code="u">Research Center Jülich</subfield>
    <subfield code="a">Ohla, Kathrin</subfield>
  </datafield>
  <datafield tag="245" ind1=" " ind2=" ">
    <subfield code="a">Recognizing taste: coding patterns along the neural axis in mammals</subfield>
  </datafield>
  <datafield tag="540" ind1=" " ind2=" ">
    <subfield code="u">https://creativecommons.org/licenses/by/4.0/legalcode</subfield>
    <subfield code="a">Creative Commons Attribution 4.0 International</subfield>
  </datafield>
  <datafield tag="650" ind1="1" ind2="7">
    <subfield code="a">cc-by</subfield>
    <subfield code="2">opendefinition.org</subfield>
  </datafield>
  <datafield tag="520" ind1=" " ind2=" ">
    <subfield code="a">&lt;p&gt;The gustatory system encodes information about chemical identity, nutritional value, and concentration of sensory stimuli before transmitting the signal from taste buds to central neurons that process and transform the signal. Deciphering the coding logic for taste quality requires examining responses at each level along the neural axis - from peripheral sensory organs to gustatory cortex. From the earliest single fiber recordings, it was clear that some afferent neurons respond uniquely, others to stimuli of multiple qualities.&amp;nbsp; There is frequently a &amp;ldquo;best stimulus&amp;rdquo; for a given neuron, leading to the suggestion that taste exhibits &amp;ldquo;labeled line coding&amp;rdquo;. In the extreme, a strict &amp;ldquo;labeled line&amp;rdquo; requires neurons and pathways dedicated to single qualities (e.g. sweet, bitter, etc.). At the other end of the spectrum, &amp;quot;across-fiber&amp;rdquo;, &amp;ldquo;combinatorial&amp;rdquo;, or &amp;ldquo;ensemble&amp;rdquo; coding requires minimal specific information to be imparted by a single neuron. Instead, taste quality information is encoded by simultaneous activity in ensembles of afferent fibers. Further, &amp;ldquo;temporal coding&amp;rdquo; models have proposed that certain features of taste quality may be embedded in the cadence of impulse activity. Taste receptor proteins are often expressed in non-overlapping sets of cells in taste buds apparently supporting &amp;ldquo;labeled lines&amp;rdquo;. Yet, taste buds include both narrowly- and broadly-tuned cells. As gustatory signals proceed to the hindbrain and on to higher centers, coding become more distributed, and temporal patterns of activity become important. Here, we present the conundrum of taste coding in the light of current electrophysiological and imaging techniques at several levels of the gustatory processing pathway.&amp;nbsp;&lt;/p&gt;</subfield>
  </datafield>
  <datafield tag="773" ind1=" " ind2=" ">
    <subfield code="n">doi</subfield>
    <subfield code="i">isVersionOf</subfield>
    <subfield code="a">10.5281/zenodo.1973233</subfield>
  </datafield>
  <datafield tag="024" ind1=" " ind2=" ">
    <subfield code="a">10.5281/zenodo.2564740</subfield>
    <subfield code="2">doi</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">publication</subfield>
    <subfield code="b">article</subfield>
  </datafield>
</record>
135
47
views
downloads
All versions This version
Views 13538
Downloads 4728
Data volume 27.7 MB17.9 MB
Unique views 11636
Unique downloads 4526

Share

Cite as