Journal article Open Access

FORMULATION AND EVALUATION OF PLURONIC LECITHIN CLOTRIMAZOLE ORGANOGEL FOR TOPICAL DELIVERY

Sandeep C Atram*, Abhilash V Joshi1, Nishan N Bobde, Vikrant P Wankhade, Dr. Shrikant D. Pande


DCAT Export

<?xml version='1.0' encoding='utf-8'?>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:adms="http://www.w3.org/ns/adms#" xmlns:cnt="http://www.w3.org/2011/content#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dct="http://purl.org/dc/terms/" xmlns:dctype="http://purl.org/dc/dcmitype/" xmlns:dcat="http://www.w3.org/ns/dcat#" xmlns:duv="http://www.w3.org/ns/duv#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:frapo="http://purl.org/cerif/frapo/" xmlns:geo="http://www.w3.org/2003/01/geo/wgs84_pos#" xmlns:gsp="http://www.opengis.net/ont/geosparql#" xmlns:locn="http://www.w3.org/ns/locn#" xmlns:org="http://www.w3.org/ns/org#" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:prov="http://www.w3.org/ns/prov#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:schema="http://schema.org/" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:vcard="http://www.w3.org/2006/vcard/ns#" xmlns:wdrs="http://www.w3.org/2007/05/powder-s#">
  <rdf:Description rdf:about="https://doi.org/10.5281/zenodo.2556491">
    <rdf:type rdf:resource="http://www.w3.org/ns/dcat#Dataset"/>
    <dct:type rdf:resource="http://purl.org/dc/dcmitype/Text"/>
    <dct:identifier rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://doi.org/10.5281/zenodo.2556491</dct:identifier>
    <foaf:page rdf:resource="https://doi.org/10.5281/zenodo.2556491"/>
    <dct:creator>
      <rdf:Description>
        <rdf:type rdf:resource="http://xmlns.com/foaf/0.1/Agent"/>
        <foaf:name>Sandeep C Atram*, Abhilash V Joshi1, Nishan N Bobde, Vikrant P Wankhade, Dr. Shrikant D. Pande</foaf:name>
        <foaf:givenName>Abhilash V Joshi1, Nishan N Bobde, Vikrant P Wankhade, Dr. Shrikant D. Pande</foaf:givenName>
        <foaf:familyName>Sandeep C Atram*</foaf:familyName>
        <org:memberOf>
          <foaf:Organization>
            <foaf:name>Vidyabharati College of Pharmacy, Amravati, Maharashtra, India, 444602.</foaf:name>
          </foaf:Organization>
        </org:memberOf>
      </rdf:Description>
    </dct:creator>
    <dct:title>FORMULATION AND EVALUATION OF PLURONIC LECITHIN CLOTRIMAZOLE ORGANOGEL FOR TOPICAL DELIVERY</dct:title>
    <dct:publisher>
      <foaf:Agent>
        <foaf:name>Zenodo</foaf:name>
      </foaf:Agent>
    </dct:publisher>
    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#gYear">2019</dct:issued>
    <dcat:keyword>Pluronic Lecithin Organogel, Clotrimazole, Topical Delivery.</dcat:keyword>
    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2019-02-04</dct:issued>
    <owl:sameAs rdf:resource="https://zenodo.org/record/2556491"/>
    <adms:identifier>
      <adms:Identifier>
        <skos:notation rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://zenodo.org/record/2556491</skos:notation>
      </adms:Identifier>
    </adms:identifier>
    <dct:isVersionOf rdf:resource="https://doi.org/10.5281/zenodo.2556490"/>
    <dct:isPartOf rdf:resource="https://zenodo.org/communities/iajpr"/>
    <dct:description>&lt;p&gt;Clotrimazole is a synthetic, imidazole derivate with broad-spectrum, antifungal drug which has been used in many skin and nail infections caused by fungi. The aim of the present study is to prepare and evaluate novel topical drug delivery of clotrimazole by using pluronic lecithin based organogel. Formulations were developed using 30% oil phase and 70% aqueous phase. The formulated organogels were evaluated for appearance by psycho-rheological, in vitro diffusion study, drug content, viscosity, spreadability and pH. It was found that the pH of all the formulations is in the range of to 6-7 that suits the skin pH, indicating skin compatibility. This is the primary requirement for a good topical formulation. All formulation showed spreadability in the range of 13.83- 28.35gcm/sec. The finding of the study can be utilize for the development of organogel of the other drugs for the safer and effective topical delivery.&lt;/p&gt;</dct:description>
    <dct:accessRights rdf:resource="http://publications.europa.eu/resource/authority/access-right/PUBLIC"/>
    <dct:accessRights>
      <dct:RightsStatement rdf:about="info:eu-repo/semantics/openAccess">
        <rdfs:label>Open Access</rdfs:label>
      </dct:RightsStatement>
    </dct:accessRights>
    <dcat:distribution>
      <dcat:Distribution>
        <dct:rights>
          <dct:RightsStatement rdf:about="https://creativecommons.org/licenses/by/4.0/legalcode">
            <rdfs:label>Creative Commons Attribution 4.0 International</rdfs:label>
          </dct:RightsStatement>
        </dct:rights>
        <dcat:accessURL rdf:resource="https://doi.org/10.5281/zenodo.2556491"/>
      </dcat:Distribution>
    </dcat:distribution>
  </rdf:Description>
</rdf:RDF>
104
112
views
downloads
All versions This version
Views 104104
Downloads 112112
Data volume 57.9 MB57.9 MB
Unique views 101101
Unique downloads 105105

Share

Cite as