Dataset Open Access

Single molecule data for unphosphorylated Aurora-A (Gilburt et al, Chemical Science 2019)

Gilburt, James AH; Ying, Liming; Dodson, Charlotte A

Raw and partially processed single molecule intensity histogram and dwell time histogram data for the following publication:

James A H Gilburt, Paul Girvan, Julian Blagg, Liming Ying, Charlotte A Dodson (2019) Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation. Chemical Science. DOI: 10.1039/c8sc03669a

Please cite our publication in any use of this data.

 

Files (31.0 GB)
Name Size
Code.zip
md5:e4342cd614909927b2ce2f9a4d659fd8
11.6 kB Download
KC SC dephosphorylated dwell times.zip
md5:33acadfcc69c25ed02b787bf28bdc6bd
9.9 GB Download
KC SC unphosphorylated CD532.7z
md5:7bf42bef2080687199efb9b5a6eee7a3
3.3 GB Download
KC SC unphosphorylated MLN8054.7z
md5:bf067c2bbf6df6f441965bd5ab8029b6
2.0 GB Download
KC SC unphosphorylated TPX2.zip
md5:94997b887723d62a234cf6981b5a754d
3.0 GB Download
KCSC unphosphorylated apo.7z
md5:0a6a57d40d624dd84372ab507df41efe
5.2 GB Download
MC SC phosphorylated apo.zip
md5:f70231fc8d53d504f0dc9cb068d0d5b1
5.4 GB Download
MC SC unphosphorylated apo.zip
md5:7539ea0505b2e353286b958ef0a5428f
2.1 GB Download
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