Journal article Open Access

Dichromacy: Color Vision Impairment and Consanguinity in Heterogenous Population of Pakistan

Akhtar, Muhammad Shoaib; Aslamkhan, Muhammad; Zar, Mian Sahib; Hanif, Asif; Haris, Abdul Rehman


DCAT Export

<?xml version='1.0' encoding='utf-8'?>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:adms="http://www.w3.org/ns/adms#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dct="http://purl.org/dc/terms/" xmlns:dctype="http://purl.org/dc/dcmitype/" xmlns:dcat="http://www.w3.org/ns/dcat#" xmlns:duv="http://www.w3.org/ns/duv#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:frapo="http://purl.org/cerif/frapo/" xmlns:geo="http://www.w3.org/2003/01/geo/wgs84_pos#" xmlns:gsp="http://www.opengis.net/ont/geosparql#" xmlns:locn="http://www.w3.org/ns/locn#" xmlns:org="http://www.w3.org/ns/org#" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:prov="http://www.w3.org/ns/prov#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:schema="http://schema.org/" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:vcard="http://www.w3.org/2006/vcard/ns#" xmlns:wdrs="http://www.w3.org/2007/05/powder-s#">
  <rdf:Description rdf:about="https://doi.org/10.5281/zenodo.2545843">
    <dct:identifier rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://doi.org/10.5281/zenodo.2545843</dct:identifier>
    <foaf:page rdf:resource="https://doi.org/10.5281/zenodo.2545843"/>
    <dct:creator>
      <rdf:Description>
        <rdf:type rdf:resource="http://xmlns.com/foaf/0.1/Agent"/>
        <foaf:name>Akhtar, Muhammad Shoaib</foaf:name>
        <foaf:givenName>Muhammad Shoaib</foaf:givenName>
        <foaf:familyName>Akhtar</foaf:familyName>
        <org:memberOf>
          <foaf:Organization>
            <foaf:name>DHQ Hospital Chakwal, Pakistan</foaf:name>
          </foaf:Organization>
        </org:memberOf>
      </rdf:Description>
    </dct:creator>
    <dct:creator>
      <rdf:Description>
        <rdf:type rdf:resource="http://xmlns.com/foaf/0.1/Agent"/>
        <foaf:name>Aslamkhan, Muhammad</foaf:name>
        <foaf:givenName>Muhammad</foaf:givenName>
        <foaf:familyName>Aslamkhan</foaf:familyName>
        <org:memberOf>
          <foaf:Organization>
            <foaf:name>Health Research Division, Sundas Foundation Lahore, Pakistan</foaf:name>
          </foaf:Organization>
        </org:memberOf>
      </rdf:Description>
    </dct:creator>
    <dct:creator>
      <rdf:Description>
        <rdf:type rdf:resource="http://xmlns.com/foaf/0.1/Agent"/>
        <foaf:name>Zar, Mian Sahib</foaf:name>
        <foaf:givenName>Mian Sahib</foaf:givenName>
        <foaf:familyName>Zar</foaf:familyName>
        <org:memberOf>
          <foaf:Organization>
            <foaf:name>School of Biology and Basic Medical Sciences, Soochow University, P.R. China</foaf:name>
          </foaf:Organization>
        </org:memberOf>
      </rdf:Description>
    </dct:creator>
    <dct:creator>
      <rdf:Description>
        <rdf:type rdf:resource="http://xmlns.com/foaf/0.1/Agent"/>
        <foaf:name>Hanif, Asif</foaf:name>
        <foaf:givenName>Asif</foaf:givenName>
        <foaf:familyName>Hanif</foaf:familyName>
        <org:memberOf>
          <foaf:Organization>
            <foaf:name>University Institute of Public Health, University of Lahore, Pakistan</foaf:name>
          </foaf:Organization>
        </org:memberOf>
      </rdf:Description>
    </dct:creator>
    <dct:creator>
      <rdf:Description>
        <rdf:type rdf:resource="http://xmlns.com/foaf/0.1/Agent"/>
        <foaf:name>Haris, Abdul Rehman</foaf:name>
        <foaf:givenName>Abdul Rehman</foaf:givenName>
        <foaf:familyName>Haris</foaf:familyName>
        <org:memberOf>
          <foaf:Organization>
            <foaf:name>National University of Medical Sciences Rawalpindi, Pakistan</foaf:name>
          </foaf:Organization>
        </org:memberOf>
      </rdf:Description>
    </dct:creator>
    <dct:title>Dichromacy: Color Vision Impairment and Consanguinity in Heterogenous Population of Pakistan</dct:title>
    <dct:publisher>
      <foaf:Agent>
        <foaf:name>Zenodo</foaf:name>
      </foaf:Agent>
    </dct:publisher>
    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#gYear">2019</dct:issued>
    <dcat:keyword>Chiniot</dcat:keyword>
    <dcat:keyword>Consanguinity</dcat:keyword>
    <dcat:keyword>Deuteranopia</dcat:keyword>
    <dcat:keyword>Dichromacy</dcat:keyword>
    <dcat:keyword>Ethnicity</dcat:keyword>
    <dcat:keyword>Heterogenous Population</dcat:keyword>
    <dcat:keyword>Pakistan</dcat:keyword>
    <dcat:keyword>Protanopia</dcat:keyword>
    <dcat:keyword>Punjab</dcat:keyword>
    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2019-01-01</dct:issued>
    <owl:sameAs rdf:resource="https://zenodo.org/record/2545843"/>
    <adms:identifier>
      <adms:Identifier>
        <skos:notation rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://zenodo.org/record/2545843</skos:notation>
        <adms:schemeAgency>url</adms:schemeAgency>
      </adms:Identifier>
    </adms:identifier>
    <dct:isVersionOf rdf:resource="https://doi.org/10.5281/zenodo.2543868"/>
    <dct:isPartOf rdf:resource="https://zenodo.org/communities/tijfs"/>
    <dct:description>&lt;p&gt;&lt;strong&gt;Abstract:&lt;/strong&gt;&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Background and Objectives:&lt;/strong&gt; Dichromacy, an X-linked recessive disorder is identified worldwide, more in males than females. In European Caucasians, its incidence is 8% in males and 0.5% in females. In India, it is 8.73% in males and 1.69% in females, and in Iran, it is 8.18% in males and 0.43% in females. Population based epidemiological data about dichromacy in different ethnic groups in Pakistan is not available. The aim of this study was to find out the population prevalence of inherited red-green dichromacy in a heterogenous population of the district of Chiniot, Punjab, Pakistan, and to determine the impact of consanguinity and ethnicity.&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Methods:&lt;/strong&gt; In this cross-sectional study, boys and girls of the higher secondary schools were examined in the three tehsils of district Chiniot. Pseudoisochromatic Ishihara Test has been employed for detection of dichromacy in the study population. The sample size was calculated statistically as 260, which was expanded to 705 and divided by population density of the three tehsils.&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Results:&lt;/strong&gt; Screening of 359 males and 346 females revealed 19 (5.29%) dichromat males and only 2 (0.58%) females. The study population belonged to 23 castes / isonym groups. The consanguinity found in the district of Chiniot is 84.82% and in the dichromat families, it is 85.71%, of which 52.37% are first cousin.&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Interpretation &amp;amp; Conclusion:&lt;/strong&gt; The study has shown that the incidence of dichromacy could be reduced through genetic counseling&lt;/p&gt;</dct:description>
    <dct:accessRights rdf:resource="http://publications.europa.eu/resource/authority/access-right/PUBLIC"/>
    <dct:accessRights>
      <dct:RightsStatement rdf:about="info:eu-repo/semantics/openAccess">
        <rdfs:label>Open Access</rdfs:label>
      </dct:RightsStatement>
    </dct:accessRights>
    <dct:license rdf:resource="https://creativecommons.org/licenses/by/4.0/legalcode"/>
    <dcat:distribution>
      <dcat:Distribution>
        <dcat:accessURL>https://doi.org/10.5281/zenodo.2545843</dcat:accessURL>
        <dcat:byteSize>1500685</dcat:byteSize>
        <dcat:downloadURL rdf:resource="https://zenodo.org/record/2545843/files/6.pdf">https://zenodo.org/record/2545843/files/6.pdf</dcat:downloadURL>
        <dcat:mediaType>application/pdf</dcat:mediaType>
      </dcat:Distribution>
    </dcat:distribution>
  </rdf:Description>
</rdf:RDF>
237
270
views
downloads
All versions This version
Views 237171
Downloads 270155
Data volume 405.2 MB232.6 MB
Unique views 164124
Unique downloads 244143

Share

Cite as