2530507
doi
10.5281/zenodo.2530507
oai:zenodo.org:2530507
user-iajpr
ANTIBIOTIC BEAD POUCHES IN OPEN FRACTURES: ELUTION OF ANTIBIOTICS FROM PMMA BEAD POUCHES IN OPEN FRACTURES
Dr S Amarnath M.S*, K Bindu Madhuri, L Tejaswi, A Chetanya Brahma, Dr Shaik Faizan Ali
Amar Orthopedic Hospital, Department of Pharmacy Practice, Hindu college of Pharmacy, Guntur.
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Antibiotic Bead Pouch, Open Fractures, Gentamicin, PMMA (Polymethyl Methacrlyte) Bone Cement.
<p>The increasing incidence of open fractures has led to higher infection rates leading to higher incidence of non-union and morbidity. Antibiotic impregnated PMMA (polymethyl methacrlyte) bone cement, (in the form of bead pouch) is used to deliver higher concentrations of local antibiotics to prevent bone infection in open fractures. This study demonstrates the effectiveness of combination antibiotic impregnated bone cement in infected open fractures. This study shows that local antibiotic elution through antibiotic impregnated bone cement is more potent and helps in controlling the infection. Combination antibiotics added to bone cement are more effective against a wide spectrum of bacteria than single antibiotic (gentamicin as provided by manufacturer).</p>
Zenodo
2018-11-30
info:eu-repo/semantics/article
2530506
user-iajpr
1579539885.43825
1160764
md5:ded94073abce269c6e11981a61f0a1ff
https://zenodo.org/records/2530507/files/12.pdf
public
10.5281/zenodo.2530506
isVersionOf
doi