2529299
doi
10.5281/zenodo.2529299
oai:zenodo.org:2529299
user-iajpr
EFFECT OF LOW DOSE KETAMINE HYDROCHLORIDE ON TOURNIQUET INDUCED HYPERTENSION IN LOWER LIMB SURGERIES
Dr. Srishti Meghare, Dr.Kinna Shah, Dr. Bhavana Shah
Anesthesia Department, G C R I, Ahmedabad, Gujarat.
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Tourniquet, Hypertension, Orthopaedic Surgery, Ketamine.
<p>Aim:-There is a constant increase in hemodynamic parameters during prolonged tourniquet inflation .We had investigated the effect of low dose 0.5mg/kg bolus ketamine on hemodynamic changes during tourniquet application in lower limb orthopaedic surgeries under general Anesthesia. Method:-100 patients posted for lower limb surgeries under standard general anesthesia using tourniquet were randomly assigned to one of two groups in double blind study. The Group C (control group) received 10 ml saline IV and Group K (study group) received 0.5mg/kg diluted in 10ml 0.9% saline IV given 10 minutes before tourniquet inflation. We had recorded hemodynamic changes, EtCO2 and Et Sevoflurane at 5 minutes interval up to 20 minutes of tourniquet deflation. Inj. Fentanyl 1mcg/kg supplemented if Systolic BP or heart rate raised more than 30% of base line. Results: - Hemodynamic stability was seen statically significant in Group K (p value, < 0.05) at 40, 50 and 60 minutes. Less number of patients needed supplemental fentanyl intra operatively in Group K than in Group C (3 V/s.18 p value <0.05). Conclusion: - Low dose bolus Ketamine 0.5mg/kg prevents tourniquet induced hypertension in lower limb surgery done under general anesthesia.</p>
Zenodo
2018-12-31
info:eu-repo/semantics/article
2529298
user-iajpr
1579537942.000835
586061
md5:619b4509df6bedd0b16ed89b5ee56fe5
https://zenodo.org/records/2529299/files/180815.pdf
public
10.5281/zenodo.2529298
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doi