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Evidence-based methodology for identifying drugs with potential human liver toxicities using US EPA ToxCast data set

Tsaioun, Katya; Bandhakavi, Sricharan; Dirven, Hubert

Researcher(s)
Sayed, Ahmed

This document describes the protocol for US EPA ToxCast data analysis. The EBTC Tox21 working group and US EPA ToxCast scientists Drs. Richard Judson, Keith Houck and Nicole Kleistreuer were consulted for comment and approval prior to publication of this protocol. Any disputes were arbitrated by the Working Group stream leaders KT and HD. The protocol was reviewed by the EBTC Board of Trustees and signed off by EBTC's Executive Director, Dr Katya Tsaioun. After sign-off, this protocol was published in the Zonodo.org repository, prior to completing of the analysis and data analysis.

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  • http://linkinghub.elsevier.com/retrieve/pii/S1359644616300411

  • http://www.hindawi.com/journals/bmri/2016/9737920/

  • https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btw680

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