2526125
doi
10.5281/zenodo.2526125
oai:zenodo.org:2526125
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A BUOYANT APPROACH FOR RETENTIVE DRUG DELIVERY: FLOATING MICROSPHERES
Soniya Kashyap*, Shikha Yadav, Popin Kumar, Tulsi Bisht
Gyani Inder Singh Institute of Professional Studies, Opp.Malsi Dear Park, Post Sinola, Dehradun, Uttarakhand, 248003, India.
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
FDDS, Buoyant, Effervescent, Non-effervescent, Polymers, Gastro retentive drug delivery.
<p>Floating drug delivery systems are low density systems that float over the gastric content and remain buoyant in the stomach for a prolonged period of time. They enhance drug bioavailability, reduce drug wastage, and provide controlled drug delivery and better patient compliance. Several approaches are currently being used to prolong the GRT, including floating drug delivery systems (FDDS), also known as hydrodynammically balanced systems (HBS), swelling and expanding systems, high density systems, and other delayed gastric emptying devices. The methodologies used in the development of FDDS by formulating effervescent and non-effervescent floating tablet based on buoyancy mechanism. Floating drug delivery systems (FDDS) was to organize the recently focus on the principal mechanism of floatation to achieve gastric retention time. This review article on FDDS includes the different types of FDDS, polymers used in formulation of FDDS, methods for manufacturing of granules, evaluation parameters.</p>
Zenodo
2017-05-31
info:eu-repo/semantics/article
2526124
user-iajpr
1579526261.914773
725559
md5:e90b4d75bd9b502c7749c4158641c581
https://zenodo.org/records/2526125/files/2.pdf
public
10.5281/zenodo.2526124
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doi