Published March 31, 2017
| Version v1
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SIO2.CAA: AN EFFICIENT CATALYST FOR ONE POT SYNTHESIS OF 4,6- DIARYLPYRIMIDINE- 2(1H)-ONES OR THIONES
- 1. Organic Chemistry Research Laboratory, Department of Chemistry, C.K.Thakur A.C.S. College New Panvel, Raigad, Maharashtra, India-410206.
Description
An efficient method for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones or thiones by using SiO2.CAA. The condensation of acetophenone, aldehydes and urea or thiourea in the presence of silica supported catalyst was employed to synthesize a variety of pyrimidinones or thiones in excellent yields. The remarkable feature of this synthetic pathway is simple workup, shorter reaction times, high yields
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