Journal article Open Access

EVALUATION OF C. ALBICANS INDUCED WOUND HEALING ACTIVITY OF METHANOLIC LEAF EXTRACT OF ANDROGRAPHIS PANICULATA

Pattiyappan Sagadevan1*, Suresh Natarajan2, Ranjithkumar Rajamani1, Chandar Shekar Bellan1, Rathishkumar Sivaraman1

To establish the wound healing activity of methanolic extract of A. paniculata two model were performed to evaluate the wound healing i.e., incision and excision model. In incision model the parameter which was carried out was breaking strength of wound skin. In excision model percentage wound concentration and period of epithelization was established for the extract. Reference stand drug was Framycetin sulphate cream ointment for comparison with other group. From the observation in both the model. Methanolic extract was found to have greater wound healing activity it terms of breaking strength in incision model and percentage wound concentration, period of epithelization was highest in excision model compared with group. In conclusion methanolic extract of A. paniculata better healing ablity.

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