Journal article Open Access

Hard palate in fetal and early neonatal periods of human ontogenesis

Slobodian, Oleksandr; Prodanchuk, Anna

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  "publisher": "Zenodo", 
  "DOI": "10.5281/zenodo.2222299", 
  "container_title": "Moldovan Medical Journal", 
  "language": "eng", 
  "title": "Hard palate in fetal and early neonatal periods of human ontogenesis", 
  "issued": {
    "date-parts": [
  "abstract": "<p><strong>Background:</strong> This investigation is important to reveal hard palate ontogenetic transformations in fetal and early neonatal periods, which is important&nbsp;for the facial surgery in fetuses, newborns.<br>\n<strong>Material and methods: </strong>Investigations have been performed in 53 cadavers of fetuses from 4 to 10 months of development, and in 9 cadavers of newborn&nbsp;children of both genders, who died of the reasons not connected with digestive system diseases or anomalies, and were without external signs of anatomic&nbsp;deviations or abnormalities, and were without evident macroscopic deviations of skull structure. Adequate anatomic methods have been used for&nbsp;investigation: macropreparations, topographic anatomical sections, morphometry, and statistical analysis.<br>\n<strong>Results: </strong>Variants of the hard palate shapes during fetal and early neonatal periods of ontogenesis are the following: trapezium (15%), square (10%), and&nbsp;ellipse (7%) shapes. The shapes of the trapezium were detected in most cases in 6-7-month fetuses (20%), and in equal percentage proportion in early&nbsp;and late fetuses (12%). The square form is a characteristic variant form in early fetuses (17%), with fetuses age increase this form was detected in less&nbsp;cases, in 6-7-month fetuses &ndash; in 10%, in late (8-10 month) fetuses &ndash; in 8%, and within the newborn period the square form was not observed. The form&nbsp;of the ellipse was observed in larger percentage proportion in late fetuses and in newborns (12%), in less proportion (5%) &ndash; in 6-7-month fetuses, in early&nbsp;fetuses this form was not detected at all. Forms of the ellipse and of the trapezium were observed in equal number of cases in 8-10-month fetuses and&nbsp;newborns. With fetuses development the hard palate form in sagittal and frontal planes changed from arcuate to flat one.<br>\n<strong>Conclusions: </strong>An ascertainment of typical and variant anatomy of hard palate forms and types would promote implementation of the new methods of&nbsp;major and reconstructive surgical invasions in face and skull.</p>", 
  "author": [
      "family": "Slobodian, Oleksandr"
      "family": "Prodanchuk, Anna"
  "page": "18-20", 
  "volume": "61(4)", 
  "type": "article-journal", 
  "id": "2222299"
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