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Policy Document on vision, scope and structure of ISBE Data Generation Centres.

Thanos, Dimitris; Kolyva, Sissy; Michalopoulos, Ioannis; Westerhoff, Hans; Steinkoetter, Jutta; Hoefer, Thomas; Mauer-Oberthuer, Angela; Sharpe, James; La Novere, Nicolas; Martins dos Santos, Vitor; Nielsen, Jens

Systems biology models require data that are fit for modeling, both when models are built and for their validation. More often than not, disparate data sets must be combined and integrated (e.g. microscopy and proteomics and metabolomics) posing severe constraints on experimental and analytical procedures. This includes issues such as precision of data, sample preparation, data acquisition protocols and data analysis methodologies. To support the life sciences community ISBE will provide access through its National System Biology Centres (nSBCs) to services of data generation facilities that are able to provide model compliant data. Either such facilities may be integrated into the nSBC, or the nSBC may liaise with such facilities provided by other infrastructures, projects or initiatives. 

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