2040342
doi
10.5281/zenodo.2040342
oai:zenodo.org:2040342
user-labscribbles
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Hutchinson, Ashley
Structural Genomics Consortium, University of Toronto
Seitova, Alma
Structural Genomics Consortium, University of Toronto
Arrowsmith, Cheryl
Structural Genomics Consortium, University of Toronto
Edwards, Aled
Structural Genomics Consortium, University of Toronto
Large scale expression and purification of full-length huntingtin Q54 with HAP40 from baculoviral expression system production in sf9 insect cells – 2018/08/04
Harding, Rachel
Structural Genomics Consortium, University of Toronto
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
huntingtin
Huntington's disease
HAP40
Protein purification
<p><strong>Project</strong> - Huntingtin structure-function open lab notebook. </p>
<p><strong>Rationale </strong>- Purified huntingtin samples with and without stabilising binding partners (HAP40) are required for use in structural and functional studies, in particular SAXS experiments. </p>
Dr. Harding is the recipient of the Huntington's Disease Society of America Berman Topper Career Development Fellowship which funds and supports this research. The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.
Zenodo
2018-08-04
info:eu-repo/semantics/other
2040341
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https://zenodo.org/records/2040342/files/Large scale expression and purification of full-length huntingtin Q54 with HAP40 from baculoviral expression system production in sf9 insect cells 20180804.docx
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