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ISBE - draft proposal on connections

Moné, Martijn; Westerhoff, Hans; Regierer, Babette; van Driel, Roel; van Nieuwpoort, Frans; Skene, Barbara; Hermjakob, Henning; Le Novère, Nicolas; Goble, Carole; Wolstencroft, Katy

This report presents  recommendations for  what  the connections  in the  infrastructure should  comprise  and  how  they should be structured  in  order to best serve  the  above  purpose. It defines interfaces  at ISBE  nodes  that  enable R&D activities to integrate seamlessly.  Connections  include  computer‐only, computer-­assisted  and  human­‐human interactions. This document also defines  ways  in which  large systems biology  tasks  can  be  optimally  partitioned over  activities  that  can  best  be    accomplished at  ISBE  nodes,  whilst  enabling  optimal  continuous  integration  through  the  connections.

Through  ISBE, large  systems biology-­‐driven community efforts become  feasible by connecting the expertise and resources of multiple different projects in past and present. This builds ISBE as a platform from which to launch large-­‐scale integrative visionary projects with great scientific and societal impact.

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