Prevalence of congenital defects among infants of Lebedinsky district Sumy region

The frequency, nosological structure and dependence on maternal age of the prevalence of congenital pathology of newborns/live births in Lebedinsky district of Sumy region were studied. The study was conducted in 2012-2016 using an epidemiological method, as well as an analysis of reporting documentation, which covers and regulates the work of Lebedinski Central Hospital. It has been established that the incidence of congenital pathology among newborns has increased by 70% over 5 years. In the general structure of congenital malformations in the newborn/live birth of the region, the predominance of non-syndromic forms of birth defects mainly associated with disorders of the development of the bone and muscular system was recorded. It was shown that during the study period, children with congenital abnormalities were given birth by women aged 25 to 36 years, and women aged 34-36 gave birth to children with congenital malformations twice as often. With increasing age of the mother, the variety of nosological forms of congenital malformations in newborns also grew. According to the results of the study, it was concluded that the nature of the prevalence of congenital pathology of live births in the area indicates the stability of the mutation process in its population. In the future, the effectiveness of prevention of congenital and hereditary diseases in newborns/live births in the area will depend on a system of preventive measures aimed primarily at improving the activities of preconceptional prevention services, prenatal diagnostics and medical genetic counseling.