Breath Acetone as Biomarker for Lipid Oxidation and Early Ketone Detection
Creators
- 1. Erica Forzani, Center for Bioelectronics and Biosensors, The Biodesign Institute at Arizona State University, 1001 S McAllister Ave, Tempe, AZ 85287, USA
Contributors
- 1. #S2, 215, Kavuri Hills Jubilee Hills, Hyderabad-500033, India
Description
Former ketone studies, including ketoacidosis (KAD), fasting ketosis (FK), nutritional
ketosis (NK), and exercis-eaffected ketosis have brought great advances to the field of
ketones. In the present work, blood, urine and breath ketone detections were evaluated
systematically. We found that breath ketone (acetone) is the ketone of choice for detecting
early stages of ketosis. In addition, acetone was correlated with respiratory quotient, and
found to be a highly sensitive non-invasive biomarker of lipid oxidation. Furthermore,
acetone was used for fast screening of ketosis or ketoacidosis in populations, and
demonstrated value upon screening a population of 48 individuals, among which a type I
diabetes case with early symptoms of KAD and FK case were identified.
Files
GJODMS-1-103.pdf
Files
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