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The role of scientific research in the field of medicines and the development of the pharmaceutical industry

Ghicavii, Victor; Stratu, Ecaterina; Coretchi, Ianos


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            <foaf:name>Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova</foaf:name>
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    <dct:title>The role of scientific research in the field of medicines and the development of the pharmaceutical industry</dct:title>
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    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#gYear">2018</dct:issued>
    <dcat:keyword>drug development</dcat:keyword>
    <dcat:keyword>implementation</dcat:keyword>
    <dcat:keyword>investments</dcat:keyword>
    <dcat:keyword>pharmaceutical companies</dcat:keyword>
    <dcat:keyword>scientific support</dcat:keyword>
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    <dct:description>&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Approximately 91% of drugs are imported, some of which are quite expensive and unaffordable for the majority of the population. The&amp;nbsp;process of drug development, i. e. the pathway from synthesis of active substance to drug, its implementation in the clinic, is quite complicated and&amp;nbsp;long-lasting, of great responsibility and particularly costly, requires enormous investment. The manufacture and implementation of the medicine in the&amp;nbsp;medical practice creates great difficulties in starting it. Pharmaceutical manufacturing companies from the country with modest profitability are unable&amp;nbsp;or unwilling to invest financial resources in scientific research &amp;ndash; an important stage in the development of medicines and in ensuring the beneficial&amp;nbsp;activity of the concerned institutions.&lt;/p&gt; &lt;p&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; National industry must be focused on the modern manufacturing medicine, competitive and effective medicines from local raw material&amp;nbsp;and first of all on the needs of the health system in the country. The situation requires insistence and can only be improved by a joint activity of specialists&amp;nbsp;in many fields (production, distribution and rational use) and strengthening the research-development and coordination forces of the scientific activities&amp;nbsp;in the country for research, development and implementation of new native original drugs, mainly based on local raw materials. Thus, in finalizing the&amp;nbsp;analysis of the role of the pharmaceutical industry in the economic development of the state, it is necessary to mention the important social aspect of it,&amp;nbsp;the close interrelation with other branches of industry, as well as the high innovation and investment capability.&lt;/p&gt;</dct:description>
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