August 21, 2018 Thesis Open Access

Nygren, Johan

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  <identifier identifierType="DOI">10.5281/zenodo.1403889</identifier>
  <creators>
    <creator>
      <creatorName>Nygren, Johan</creatorName>
      <givenName>Johan</givenName>
      <familyName>Nygren</familyName>
      <affiliation>Unaffiliated</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Introgression from Gorilla caused the Human-Chimpanzee split</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2018</publicationYear>
  <subjects>
    <subject>evolution; human; chimpanzee; gorilla; introgression</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2018-08-21</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Thesis</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/1403889</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.1401019</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;ABSTRACT: The Gorilla Genome Project (Scally, 2012) showed that 30% of the gorilla genome introgressed into the ancestor of humans and chimpanzees, and that the two species diverged through lineage sorting with 15% ending up in &lt;em&gt;Pan&lt;/em&gt; and another 15% in &lt;em&gt;Homo&lt;/em&gt;. That introgression is the &lt;em&gt;Pan&lt;/em&gt;-&lt;em&gt;Homo&lt;/em&gt; split, hybridization, which led to speciation as the new hybrid lineages became reproductively isolated from one another.&lt;br&gt;
&lt;br&gt;
The NUMT on chromosome 5 (&amp;ldquo;ps5&amp;rdquo;) (Popadin, 2017) fits perfectly with the introgression speciation model, it was formed from mtDNA that had diverged from the common ancestor of &lt;em&gt;Pan&lt;/em&gt;-&lt;em&gt;Homo&lt;/em&gt; for 1.8 Myr at the time of insertion into the nuclear genome, and originated in the &lt;em&gt;Gorilla&lt;/em&gt; lineage. The ps5 pseudogene was transferred to &lt;em&gt;Pan&lt;/em&gt; and &lt;em&gt;Homo&lt;/em&gt; during the introgression event that led to the &lt;em&gt;Pan&lt;/em&gt;-&lt;em&gt;Homo&lt;/em&gt; split, 6 million years ago.&lt;/p&gt;</description>
  </descriptions>
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