Thesis Open Access
Nygren, Johan
<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd"> <identifier identifierType="DOI">10.5281/zenodo.1403889</identifier> <creators> <creator> <creatorName>Nygren, Johan</creatorName> <givenName>Johan</givenName> <familyName>Nygren</familyName> <affiliation>Unaffiliated</affiliation> </creator> </creators> <titles> <title>Introgression from Gorilla caused the Human-Chimpanzee split</title> </titles> <publisher>Zenodo</publisher> <publicationYear>2018</publicationYear> <subjects> <subject>evolution; human; chimpanzee; gorilla; introgression</subject> </subjects> <dates> <date dateType="Issued">2018-08-21</date> </dates> <resourceType resourceTypeGeneral="Text">Thesis</resourceType> <alternateIdentifiers> <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/1403889</alternateIdentifier> </alternateIdentifiers> <relatedIdentifiers> <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.1401019</relatedIdentifier> </relatedIdentifiers> <rightsList> <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights> <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights> </rightsList> <descriptions> <description descriptionType="Abstract"><p>ABSTRACT: The Gorilla Genome Project (Scally, 2012) showed that 30% of the gorilla genome introgressed into the ancestor of humans and chimpanzees, and that the two species diverged through lineage sorting with 15% ending up in <em>Pan</em> and another 15% in <em>Homo</em>. That introgression is the <em>Pan</em>-<em>Homo</em> split, hybridization, which led to speciation as the new hybrid lineages became reproductively isolated from one another.<br> <br> The NUMT on chromosome 5 (&ldquo;ps5&rdquo;) (Popadin, 2017) fits perfectly with the introgression speciation model, it was formed from mtDNA that had diverged from the common ancestor of <em>Pan</em>-<em>Homo</em> for 1.8 Myr at the time of insertion into the nuclear genome, and originated in the <em>Gorilla</em> lineage. The ps5 pseudogene was transferred to <em>Pan</em> and <em>Homo</em> during the introgression event that led to the <em>Pan</em>-<em>Homo</em> split, 6 million years ago.</p></description> </descriptions> </resource>
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