August 21, 2018 Thesis Open Access

Nygren, Johan

DCAT Export

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        <foaf:name>Nygren, Johan</foaf:name>
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    <dct:title>Introgression from Gorilla caused the Human-Chimpanzee split</dct:title>
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    <dcat:keyword>evolution; human; chimpanzee; gorilla; introgression</dcat:keyword>
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    <dct:description>&lt;p&gt;ABSTRACT: The Gorilla Genome Project (Scally, 2012) showed that 30% of the gorilla genome introgressed into the ancestor of humans and chimpanzees, and that the two species diverged through lineage sorting with 15% ending up in &lt;em&gt;Pan&lt;/em&gt; and another 15% in &lt;em&gt;Homo&lt;/em&gt;. That introgression is the &lt;em&gt;Pan&lt;/em&gt;-&lt;em&gt;Homo&lt;/em&gt; split, hybridization, which led to speciation as the new hybrid lineages became reproductively isolated from one another.&lt;br&gt; &lt;br&gt; The NUMT on chromosome 5 (&amp;ldquo;ps5&amp;rdquo;) (Popadin, 2017) fits perfectly with the introgression speciation model, it was formed from mtDNA that had diverged from the common ancestor of &lt;em&gt;Pan&lt;/em&gt;-&lt;em&gt;Homo&lt;/em&gt; for 1.8 Myr at the time of insertion into the nuclear genome, and originated in the &lt;em&gt;Gorilla&lt;/em&gt; lineage. The ps5 pseudogene was transferred to &lt;em&gt;Pan&lt;/em&gt; and &lt;em&gt;Homo&lt;/em&gt; during the introgression event that led to the &lt;em&gt;Pan&lt;/em&gt;-&lt;em&gt;Homo&lt;/em&gt; split, 6 million years ago.&lt;/p&gt;</dct:description>
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